超声心动图对代谢综合征患者心脏结构及功能的临床评价

ECHOCARDIOGRAPHY IN EVALUATING CARDIAC STRUCTURE AND FUNCTIONS OF PATIENTS WITH METABOLIC SYNDROME

目的探讨超声心动图对代谢综合征(MS)患者左心室肥厚(LVH)及功能的评价。方法选择45例代谢综合征患者(HMS)、42例单纯高血压患者(EH),30例健康体检者作为对照组,测定三组超声心动图的各种参数,计算左心室质量指数(LVMI)和相对室壁厚度(RWT)。于心尖四腔、心尖两腔和心尖三腔切面获得组织速度成像(TVI),应用变率成像(SRI)技术分析左室各节段心肌的应变率曲线,计算左室收缩期、舒张早期、舒张晚期峰值应变率平均值(mSRs、mRSe、mSRa)。结果高血压患者mSRs、mSRe及SRe/Sra显著低于对照组(P<0.05),HMS组与EH组比较:LVH的比率明显升高(P<0.05),而mSRs、mSRe及SRe/SRa明显降低(P<0.05)。结论超声心动图可以了解代谢综合征(MS)患者左心室肥厚(LVH)血流动力学异常,准确评价左心室心肌功能,为临床治疗提供可靠依据。

Objective To explore the echocardiography in evaluating left ventricular hypertrophy （LVH） and cardiac functions of patients with metabolic syndrome （MS） .Methods 45 patients with the metabolic syndrome group ,42 patients with simple hypertension and 30 cases of healthy cases were selected to deter-mine the various parameters of the ultrasonic cardiogram and to calculate the left ventricular mass index （LVMI） and the relative wall thickness （RWT） .Tissue velocity imaging （TVI） for the cross sections of the two cavities ,three cavities and four cavities of cardiac apex was conducted .The strain rate imaging （SRI） analysis of the left ventricular myocardial strain rate curve of each segment was conducted ,and the normal control group ,the peak values of the left ventricular systolic phase ,early diastolic phase and late diastolic phase were significantly lower （ P 〈 0 .05） .When the patients with metabolic syndrome were compared with the high blood pressure group ,the ratio of LVH increased significantly （ P〈 0 .05） ,while the peak values of the left ventricular systolic phase ,early diastolic phase and late diastolic phase signifi-cantly decreased （ P〈 0 .05） .Conclusion Echocardiography can be used to monitor the LVH hemodynam-ic abnormalities of patients with MS and to evaluate the left ventricular myocardial functions .