联合MR动态增强扫描、弥散加权成像在乳腺良恶性病变诊断中的应用价值

Application of dynamic contrast-enhanced MR scan combined with DWI in diagnosis of benign and malignant breast disease

目的探讨MR动态增强扫描、弥散加权成像及其联合应用在乳腺良恶性病变诊断中的应用价值。方法选择71例乳腺病变患者,另选择50名健康志愿者为对照组。所有纳入对象均接受磁共振常规扫描、增强扫描、弥散加权成像。计算不同方法诊断乳腺良恶性疾病的敏感度、特异度、阳性预测值、阴性预测值。结果 MR形态学在乳腺良恶性诊断中敏感度90.0%,特异度73.7%,阳性预测值78.3%,阴性预测值87.5%。乳腺多期动态增强扫描对乳腺癌良恶性诊断的敏感度92.5%,特异度66.4%,阳性预测值74.0%,阴性预测值89.3%。联合形态学、强化表现、DWI对乳腺良恶性病变诊断的敏感度95.0%,特异度89.5%,阳性预测值90.5%,阴性预测值94.4%。结论联合形态学、强化表现、DWI对乳腺良恶性病变进行诊断能够显著提高诊断的敏感度、特异度、阳性预测值以及阴性预测值。

Objective To discuss application of dynamic contrast-enhanced MR scan combined with DWI in diagnosis of benign and malignant breast disease. Methods A total of 71 cases with breast disease and 50 healthy volunteers were selected. All subjects received MRI conventional scanning, conventional scanning and DWI, sensitivity, specificity, the positive predictive value and the negative predictive value of different methods for diagnosis of benign and malig-nant breast disease. Results MR morphology in diagnosis of benign and malignant breast disease, sensitivity was 90.0%, specificity was 73.7%, the positive predictive value was 78.3%, the negative predictive value was 87.5%. Dy-namic contrast-enhanced MR scan in diagnosis of benign and malignant breast disease, sensitivity was 92.5%, speci-ficity was 66.4%, the positive predictive value was 74.0%, the negative predictive value was 89.3%. Dynamic con-trast-enhanced MR scan combined with DWI and MR morphology in diagnosis of benign and malignant breast disease, sensitivity was 95.0%, specificity was 89.5%, the positive predictive value was 90.5%, the negative predictive value was 94.4%. Conclusion Dynamic contrast-enhanced MR scan combined with DWI and MR morphology in diagnosis of benign and malignant breast disease can improve sensitivity, specificity, the positive predictive value and the negative predictive value.