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小鼠ST2基因慢病毒表达载体的构建及鉴定 被引量：5

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摘要 ST2是白细胞介素-1（interleukin-1,IL-1）受体家族的一员,是IL-33的受体。它最初是在成纤维细胞增殖的初期阶段发现的一个基因,也被称为T1,Fit-1。由于剪切和拼接方式的不同,ST2在人体内有跨膜型ST2（transmembrane ST2 isoform,ST2L）、可溶型ST2（soluble ST2,sST2）及ST2变体内有跨膜型ST2（transmembrane ST2 isoform，ST2L）。
作者 高巧艳 李燕 高雪明 袁仙丽 彭笑 周密 李明才
机构地区 宁波大学医学院免疫学研究室
出处 《细胞与分子免疫学杂志》 CAS CSCD 北大核心 2014年第9期944-947,共4页 Chinese Journal of Cellular and Molecular Immunology
基金 国家自然科学基金(81370166 81070034) 宁波市科技创新团队项目(2011B82014) 宁波市重点学科项目(XKL11D2112 XKL11D2113) 宁波大学研究生科研创新基金(G13067) 宁波大学创新性开放实验项目建设专项经费(cxxkf2013-016)
关键词 ST2 慢病毒 构建 鉴定
分类号 R392 [医药卫生—免疫学]
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参考文献15

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  • 3Bergers G, Reikerstorfer A, Braselmann S, et al. Alternative promoter usage of the Fos-responsive gene Fit-1 generates mRNA isoforms coding for either secreted or membrane-bound proteins related to the IL-1 receptor[J]. EMBO J, 1994, 13(5): 1176-1188.
  • 4Martinez-Martinez E, Miana M, Jurado-Lopez R, et al. A role for soluble ST2 in vascular remodeling associated with obesity in rats [J/OA]. PLoS One, 2013, 8(11) : e79176.
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二级参考文献2

共引文献9

同被引文献39

  • 1徐晓明,杨慧,王晓萍.慢病毒载体的构建及优化[J].中国临床康复,2006,10(9):147-149. 被引量：11
  • 2Masanori Tohno,Tomoyuki Shimazu,Hisashi Aso,Yasushi Kawai,Tadao Saito,Haruki Kitazawa.Molecular Cloning and Functional Characterization of Porcine MyD88 Essential for TLR Signaling[J].Cellular & Molecular Immunology,2007,4(5):369-376. 被引量：20
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  • 6Tang C,Lin H, Wu Q, et al. Recombinant human augmenter of liver regeneration protects hepatoeyte mitochondrial DNA in rats with obstructive jaundice[J]. J Surg Res, 2015,196 (1) :90-101.
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  • 8Prieto C,Fontana I), Etcheverrigaray M, et al. A strategy to obtain recombinant cell lines with high expression levels. Lentiviral vector-mediated transgenesis[J]. BMC Proc, 2011, 8..7.
  • 9Liu S, Liu X, Wang H, et al. Lentiviral vector-mediated doxycycline-inducible USP39 shRNA or cDNA expression in triple-negative breast cancer cells [J]. Oncol Rep, 2015, 33 (5) : 2477-2483.
  • 10廖张元,叶静,关云谦,张愚,尤小凡,安静,张颖,王淑艳,李存江.水通道蛋白4慢病毒表达载体的构建与临床应用[J].中华医学杂志,2010,90(3):208-212. 被引量：8

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细胞与分子免疫学杂志
2014年 第9期

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