期刊文献+
任意字段
题名或关键词
题名
关键词
文摘
作者
第一作者
机构
刊名
分类号
参考文献
作者简介
基金资助
栏目信息

系统性红斑狼疮患者血清IL-18、IL-8水平观察 被引量：2

下载PDF
导出
摘要 系统性红斑狼疮（systemic lupus erythematosus,SLE）是一种可累及多种系统、原因不明的自身免疫性疾病。临床表现为血清中出现多种自身抗体,常累及肾脏,引起狼疮性肾炎,最后导致患者死亡[1]。据报道70%的SLE患者有肾脏受损的表现,引发狼疮性肾炎（lupus nephritis,LN）,严重者可导致肾功能衰竭[2]。
作者 李旭光 徐燕 陈娟 费佳
机构地区 解放军
出处 《细胞与分子免疫学杂志》 CAS CSCD 北大核心 2014年第10期1093-1094,共2页 Chinese Journal of Cellular and Molecular Immunology
关键词 系统性红斑狼疮患者 白细胞介素-18 白细胞介素-8
分类号 R392.11 [医药卫生—免疫学]
  • 相关文献

参考文献15

  • 1高丽霞,张明峰,郭惠芳,靳洪涛,孙毅锋.狼疮肾炎中Th17细胞相关细胞因子的变化[J].中国免疫学杂志,2011,27(9):828-831. 被引量：6
  • 2李薇,肖影辉,王晓东,哈地丽亚,惠艳.SLE患者血清IL-10、IL-18检测及临床意义[J].新疆医学,2012,42(3):1-4. 被引量：5
  • 3ScheUekens GA, Visser H, De Jong BA, et al. The diagnostic properties of rheumatoid arthritis antibodies recognizing a cyclic citrullinated peptide [ J ]. Arthritis Rheum, 2000, 43 ( 1 ) : 155 - 163.
  • 4Yap DY, Lai KN. The role of cytokines in the pathogenesis of systemic lupus erythematosus-from bench to bedside [ J]. Nephrology (Carlton), 2013, 18(4): 243 -255.
  • 5Xu WD, Pan HF, Ye DQ. Association of interleukin-18 and systemic lupus erythematosus [ J ]. Rheumatol Int, 2013, 33 ( 12 ) : 3055 - 3057.
  • 6Sun W, Jiao Y, Cui B, et al. Immune complexes activate human endothelium involving the cell-signalingHMGB1-RAGE axis in the pathogeuesis of lupus vasculitis [ J ]. Lab Invest, 2013, 93 ( 6 ) : 626 - 638.
  • 7Kahlenberg JM, Thacker SG, Berthier CC, et al. Inilammasome activation of IL-18 results in endothelial progenitor cell dysfunction in systemic lupus erythematosus [ J ]. J Immunol, 2011, 187 ( 11 ) : 6143 - 6156.
  • 8Duan Z, Zhang Y, Zeng Z, et al. Comment on "Inflammasome activation of IL-18 results in endothelial progenitor cell dysfunction in systemic lupus erythematosus" [ J]. J Immunol, 2012, 189 ( 2 ) : 499 - 500.
  • 9Slimizu C, Fujita T, Fuke Y, et al. High eiretflafing levels d interleukin-18 protein indicate the severity of gton'tmflar involvemmt in systemic lupus erythematosus[ J]. Med Rheumatol, 2012, 22( 1 ): 73- 79.
  • 10F, Vaisi-Raygani A, Kiani A, et al. Man-ix metallolxeinase-2 functional promoter polymorphism G1575A is associated with elevated circulatory MMpo2 levels and increased risk of cardiovascular disease in systemic lupus erythematosus patients[ J]. Lupus, 2012, 21 (6) : 616 -624.

二级参考文献12

  • 1王晓非,刘海娜,蒋莉,张榕,张晓莉,郭韵,段红梅.狼疮肾炎患者血中巨噬细胞衍生趋化因子和IL-18水平的变化及意义[J].细胞与分子免疫学杂志,2006,22(6):767-768. 被引量：5
  • 2Masutani K,Akahoshi M,Tsuruya K,et al.Predominance of Th1 immune response in diffuse proliferative lupus nephritis[J].Arthritis Rheum,2001,44(9):2097.
  • 3Liew FY,McInnes IB.Role of interleukin 15 and interleukin 18 in inflammatory response[J].Ann Rheum Dis,2002,60(2):100.
  • 4Calvani N,Richards HB,Tucci M,et al.Up-regulation of IL-18 and predominance of a Th1 immune response is a hallmark of lupus nephritis[J].Clin Exp Immunol,2004,138(1):171.
  • 5Wong CK,Ho CY,Li EK,et al.Elevated production of interleukin-18 is associated with renal disease in patients with systemic lupus erythematosus[J].Clin Exp Immunol,2002,130(2):345.
  • 6Laurie S. Davis, Jack Hutcheson, Chandra Mohan. The Role of Cytokines in the Pathogenesis and Treatment of Systemic Lupus Erythematosus [ J]. Journal of interferon & cytokine research, 2011 ;10(31) ,1 -9.
  • 7Grondal G, Traustadottir KH, Kristjansdottir H, et al. Increased T - lymphocyte apoptosis/necrosis and IL - 10 producing ceils in patients and- their spouses in Icelandic systemie lupus erythematosus multiease families [ J ]. Lupus, 2002 ; 11 (7) :435 -442.
  • 8C. T. Ravirajan, Y. Wang, L. A. Mats, et al. , "Effect of neutralizing antibodies to IL - 10 and C5 on the renal damage caused by a pathogenic human anti - ds DNA antibody," Rheumatology 2004 ;43 (4) :442 - 447.
  • 9汪丽娟,黎音,孙振柱,刘晖,冷东明,王春.IL-18及IL-13在系统性红斑狼疮患者肾组织中的表达及意义[J].新疆医学,2008,38(2):5-9. 被引量：3
  • 10系统性红斑狼疮诊断及治疗指南[J].中华风湿病学杂志,2010,14(5):342-346. 被引量：554

共引文献10

同被引文献15

二级引证文献7

细胞与分子免疫学杂志
2014年 第10期

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部