期刊文献+
任意字段
题名或关键词
题名
关键词
文摘
作者
第一作者
机构
刊名
分类号
参考文献
作者简介
基金资助
栏目信息

急性缺血性脑卒中后高血糖的研究进展 被引量：14

Recent advance in hyperglycemia after acute ischemic stroke
原文传递
导出
摘要 脑卒中是我国目前第一大死亡病因及成年人首位致残原因[1].缺血性脑卒中占所有脑卒中的70％～80％,是严重危害人类健康的致死性和致残性疾病.糖尿病患病率目前在我国呈逐年上升趋势,糖尿病引起的慢性并发症,尤其大、中血管并发症,是严重影响患者生活质量和缩短患者寿命的重要原因.近年来大量研究表明,高血糖与缺血性脑卒中之间存在密切的内在联系：一方面,高血糖是缺血性脑卒中的独立危险因素,高血糖患者发生缺血性脑卒中的风险高于血糖正常者2倍以上,且该类患者在缺血性脑卒中发作后的临床表现、脑梗死体积、病死率、致残率及脑卒中复发率等方面也均更为显著[2-3];另一方面,缺血性脑卒中患者中糖代谢异常的发生率亦显著高于一般人群,且脑卒中本身所导致的应激反应可同时干扰糖代谢、诱导血糖升高.
作者 彭玲梅 姜晓丹
机构地区 佛山市第一人民医院神经内科 广州
出处 《中华神经医学杂志》 CAS CSCD 北大核心 2014年第9期969-972,共4页 Chinese Journal of Neuromedicine
基金 国家自然科学基金（81171179,81272439） 广东省科技计划重点项目（S2013020012754） 广东省教育厅实验室滚动项目（2013CXZDA008）
关键词 缺血性脑卒中 高血糖 糖尿病 Cerebral ischemia Hyperglycemia Diabetes mellitus
分类号 R743.3 [医药卫生—神经病学与精神病学]
  • 相关文献

参考文献24

  • 1Luitse MJ, Biessels GJ, Rutten GE, et al. Diabetes, hyperglycaemia, and acute ischaemic stroke [J]. Lancet Neurol, 2012, 11 (3): 261-271.
  • 2Capes SE, Hunt D, Malmberg K, et al. Stress hyperglycemia and prognosis of stroke in nondiabetic and diabetic patients: a systematic overview[J]. Stroke, 2001, 32(10): 2426-2432.
  • 3Muir KW, McCormick M, Baird T, et al. Prevalence, predictors and prognosis of post-stroke hyperglycaemia in acute stroke trials: individual patient data pooled analysis from the Virtual International Stroke Trials Archive (VISTA)[J]. Cerebrovascular Diseases Extra, 2011, 1(1): 17-27.
  • 4Emerging Risk Factors Collaborationl, Sarwar N, Gao P, et al. Diabetes mellitus, fasting blood glucose concentration, and risk of vascular disease: a collaborative meta-analysis of 102 prospective studies[J]. Lancet, 2010, 375(9733): 2215-2222.
  • 5Dungan KM, Braithwaite SS, Preiser JC. Stress hyperglycaemia[J]. Lancet, 2009, 373(9677): 1798-1807.
  • 6Kruyt ND, Biessels GJ, Devries JH, et al. Hyperglycemia in acute ischemic stroke: pathophysiology and clinical management[J]. Nat Rev Neurol, 2010, 6(3): 145-155.
  • 7Lee M, Saver JL, Hong KS, et al. Effect ofpre-diabetes on future risk of stroke: meta-analysis[J]. BMJ, 2012, 344: e3564.
  • 8Selvin E, Steffes MW, Zhu H, et al. Glycated hmoglobin, diabetes, and cardiovascular risk in nondiabetic adults [J]. N Engl J Med, 2010, 362(9): 800-811.
  • 9MacDougall NJ, Muir KW. Hyperglycaemia and infarct size inanimal models of middle cerebral artery occlusion: systematic review and meta-analysis[J]. J Cereb Blood Flow Metab, 2010, 31 (3): 807-818.
  • 10Lansberg MG, Albers GW, Wijman CA. Symptomatic intracerebral hemorrhage following thrombolytic therapy for acute ischemic stroke: a review of the risk factors[J]. Cerebrovasc Dis, 2007, 24(1): 1-10.

二级参考文献48

  • 1McCall AL. Cerebral glucose metabolism in diabetes mellitus. Eur J Pharmacol, 2004,490 : 147-158.
  • 2Matz K, Keresztes K, Tatschl C, et al. Disorders of glucose metabolism in acute stroke patients: an underrecognized problem. Diabetes Care, 2006,29:792-797.
  • 3Kernan WN, Viscoli CM, Inzucchi SE, et al. Prevalence of abnormal glucose tolerance following a transient ischemic attack or ischemic stroke. Arch Intern Med. 2005,165:227-233.
  • 4Ivey FM, Ryan AS, Hafer-Macko CE, et al. High prevalence of abnormal glucose metabolism and poor sensitivity of fasting plasma glucose in the chronic phase of stroke. Cerebrovasc Dis, 2006,22 : 368-371.
  • 5Vaneheri F, Curcio M, Burgio A, et al. Impaired glucose metabolism in patients with acute stroke and no previous diagnosis of diabetes mellitus. QJM, 2005,98:871.
  • 6Jia WP, Pang C, Chen L, et al. Epidemiological characteristics of diabetes mellitus and impaired glucose regulation in a Chinese adult population: the Shanghai Diabetes Studies, a cross-sectional 3-year follow-up study in Shanghai urban communities. Diabetologia, 2007,50:286-292.
  • 7Hu DY, Pan CY, Yu J, et al. The relationship between coronary artery disease and abnormal glucose regulation in China: the China Heart Survey. Eur Heart J, 2006,27:2573-2579.
  • 8Stratton IM, Adler AI, Neil HA, et al. Association of glycaemia with macrovascular and microvascular complications of type 2 diabetes ( UKPDS 35 ) : prospective observational study. BMJ, 2000,321:405-412.
  • 9Myint PK, Sinha S, Wareham N J, et al. Glycated hemoglobin and risk of stroke in people without known diabetes in the European Prospective Investigation into Cancer ( EPIC ) -Norfolk prospective population study: a threshold relationship? Stroke, 2007,38:271- 275.
  • 10Baird TA, Parsons MW, Barber PA, et al. The influence of diabetes mellitus and hyperglycaemia on stroke incidence and outcome. J Clin Neurosci, 2002,9:618-626.

共引文献15

同被引文献136

引证文献14

二级引证文献155

中华神经医学杂志
2014年 第9期

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部