3D-OCT引导下多波长激光治疗CSCR的疗效观察

Multiwavelength laser treatment of the central serous chorioretinopathy by 3 D-OCT guidance

目的:观察3D-OCT引导下多波长激光治疗中心性浆液性脉络膜视网膜病变(central serous chorioretinopathy,CSCR)的疗效。方法:收集2010-07/2013-07在长春爱尔眼科医院的典型性中心性浆液性脉络膜视网膜病变患者23例23眼,利用3D-OCT模式定位中心性浆液性脉络膜视网膜病变渗漏点行多波长激光光凝治疗。术后随访24wk,观察术后视力、黄斑区神经上皮层浆液性脱离高度。结果:中心性浆液性脉络膜视网膜病变患者23例23眼经3D-OCT引导下多波长激光治疗后随访24wk,治疗后视力与治疗前相比较,有统计学意义(P<0.05)。治疗前后OCT黄斑区神经上皮层脱离高度比较,有统计学意义(P<0.05),治疗后OCT黄斑区神经上皮层脱离高度明显下降,浆液明显吸收。23例23眼中心性浆液性脉络膜视网膜病变患者除1例失访者外均未见全身或眼局部不良反应的发生。结论:3D-OCT引导下多波长激光治疗中心性浆液性脉络膜视网膜病变与FFA指导下激光治疗中心性浆液性脉络膜视网膜病变效果相当,有一定的临床应用价值。

AIM：To introduce a new method of guiding by using 3D-OCT to treatment central serous chorioretinopathy （ CSCR） with multiwavelength laser. METHODS：Twenty-three cases （ 23 eyes ） typicality central serous chorioretinopathy were collected in July 2010 to July 2013 in Changchun Aier Eye Hospital, using 3D-OCT model locate central serous chorioretinopathy leakage point and photocoagulation treatment with multiwavelength laser. Postoperative follow-up of 24wk, the postoperative vision and macular area retina neuroepithelial layer detachment height were observed.RESULTS： Twenty-three cases （ 23 eyes ） of central serous chorioretinopathy patients by the 3D-OCT guided multiwavelength laser treatment vision after 24wk of follow-up compared with before treatment. there was statistically significant （ P 〈 0.05 ） . Visual improved obviously after treatment. OCT macular area before and after the treatment on macular area retina neuroepithelial layer detachment height （ P〈0.05 ） . OCT macular area before and after the treatment of macular area retina neuroepithelial layer detachment height significantly decreased, slurry apparent absorption. Except 1 case lost visitors, 23 cases （ 23 eyes ） with central serous chorioretinopathy did not see the whole body or eye local adverse reactions occur. CONCLUSION： 3D- OCT guided by multiwavelength laser treatment of central serous chorioretinopathy and under the guidance of FFA in the central serous chorioretinopathy laser treatment have the same curative ratio, has certain clinical value.