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新辅助化疗方案在乳腺癌治疗中的应用效果观察 被引量:3

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摘要 目的探讨新辅助化疗方案在乳腺癌治疗中的疗效和毒副反应。方法我院2012年6月—2013年9月收治的60例乳腺癌患者分为观察组30例,采用多西紫杉醇联合表柔比星进行化疗;对照组30例,采用环磷酰胺、表柔比星、氟尿嘧啶化疗,观察2组的疗效和毒副反应。结果观察组10例患者完全缓解,12例患者部分缓解,7例患者稳定,1例恶化,总有效率为73%;对照组10例患者完全缓解,8例患者部分缓解,8例患者稳定,4例恶化,总有效率为60%,2组比较差异有显著性(P<0.05)。结论新辅助化疗方案在乳腺癌的治疗中疗效明显,耐受良好,效果优于联合治疗乳腺癌的化疗方案。
作者 柴小郁
机构地区 洪洞县人民医院
出处 《基层医学论坛》 2014年第29期3960-3961,共2页 The Medical Forum
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  • 1李非,许红霞.新辅助化疗NP方案与FEC方案治疗乳腺癌122例比较[J].中国肿瘤,2007,16(4):291-292. 被引量:2
  • 2Kaufmann M,Hortobagyi G N,Goldhirsch A,et al.Recommendations from an international expert panel on the use of neoadjuvant(primary)systemic treatment of operable breast cancer:an update[J].J Clin Oncol,2006,24(12):1940-1949.
  • 3Mamounas E P.NSABP protocol B-27.Preoperative doxorubicin plus cyclophosphamide followed by preoperative or postoperative docetaxel[J].Oncology(WilIiston Park),1997,11(6 Suppl 6):37-40.
  • 4van der Hage J A,van de Velde C J,Julien J P,et al.Preoperative chemotherapy in primary operable breast cancer:results from the European Organization for Research and Treatment of Cancer trial 10902[J].J Clin Oncol,2001,19(22):4224-4237.
  • 5Fisher E R,Wang J,Bryant J,et al.Pathobiology of preoperative chemotherapy:findings from the National Surgical Adjuvant Breast and Bowel(NSABP)protocol B-18[J].Cancer,2002,95(4):681-695.
  • 6Chaffare H,Limongelli S,Purushotham A D.Neoadjuvant chemotherapy in breest cancer[J].Br J Surg,2005,92(1):14-23.
  • 7Hurvitz S,Dirsx L,Kocsis J,et al. Trastuzumab emtansine(T - DM1 ) vs trastuzumab plus docetaxel in muhicenter, open - label, phase II study [ A ]. European Muhidisciplinary Cancer Congress,2011, Stockholm.
  • 8Bonadonna G, Zambtti M, Valagussa P. Sequential or alternating doxoru- bicin and CMF regimens in breast cancer with more than three positive nodes [ J ]. JAMA, 1995,273 ( 7 ) :542 -547.
  • 9Untch M, M~bus V, Kuhn W, et al. Intensive cose - dense compared with conventionally scheduled preoperative chemotherapy for high - risk primary breast cancer[ J]. J Clin Onco1,2009,27 ( 18 ) :2938-2945.
  • 10Untch M, Fasching A, Konecny E, et al. A randomized phase III trial comparing preoperative, dose - dense, dose - intensified chemotherapy with epirubicin,paclitaxel and CMF versus a standard -dosed epirubicin/cyclophosphamide followed by paclitaxel ± darbepoetin alfa in pri- mary breast cancer-results at the time of surgery [ A ]. European Multi- disciplinary Cancer Congress,2011, Stockholm.

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