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DNA甲基化与动脉粥样硬化的研究进展

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摘要 动脉粥样硬化(AS)的基因水平研究主要集中在表观遗传学方面。DNA甲基化作为表观遗传学的重要组成部分,在AS的病理机制中逐步被认识。该文就近年来AS相关的雌激素受体、p53、细胞外超氧化物歧化酶(EC-SOD)、15脱氧化酶(ALOX15)、叉头样转录因子(FOXP3)、凝血因子Ⅶ(F7)和PLA2G7等基因的DNA甲基化与AS的关系作一综述。
作者 乔鑫 彭瑜 张钲
机构地区 兰州大学附属第一医院心血管内科
出处 《国际心血管病杂志》 2014年第5期297-299,共3页 International Journal of Cardiovascular Disease
基金 国家临床重点科室项目(2013)
关键词 表观遗传学 DNA甲基化 动脉粥样硬化
分类号 R543.5 [医药卫生—心血管疾病]
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参考文献20

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国际心血管病杂志
2014年 第5期

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