MR T_2 mapping在肌肉疾病中的应用价值

The value of MR T_2-mapping in muscular disorders

MRI因其多平面、多序列、高分辨力等特点对肌肉组织疾病的诊断具有重要价值,特别是近年新发展起来的MRI T2mapping技术,不但能从分子水平评价关节软骨和椎间盘、中枢神经系统损伤及退化性疾病、肿瘤良恶性等情况,还逐渐应用于肌肉组织成像。T2mapping可以通过测量组织T2值来定量分析组织内部成分的变化,在疾病早期准确诊断、病情发展程度和疗效的判断上发挥重要作用。就T2mapping的基本原理及在肌肉疾病中的研究应用进展予以综述。

MRI is of important value to the diagnosis of muscular diseases due to its multiple planes, multiple sequences, high resolution, etc. T2 mapping is a new emerging technology of MRI and is mainly used to evaluate articular cartilage and intervertebral disc at the molecular level, central nervous system damage and degenerative diseases, and benign and malignant tumors. In recent years, it has been gradually applied in muscle tissue imaging. T2 mapping can quantificationally analyze the changes in composition of the organization by measuring T2 relaxation time, and it plays important roles in early and accurate diagnosis, prediction of disease development and evaluation of therapeutic effect. The basic principle of T2 mapping and the progress of its research application in muscle diseases were reviewed.