糖尿病肾病中医分型与血清hs-CRP、ABI的相关性研究

Research on Correlation Between TCM Types and hs-CRP,ABI in Patients With Diabetic Nephropathy

目的观察糖尿病肾病中医分型与血清超敏C反应蛋白(hs-CRP)、踝臂指数(ABI)的相关性。方法 118例糖尿病肾病患者作为观察组,40例健康人作为对照组,并且对糖尿病肾病患者进行中医分型。测定所有人血清hs-CRP和ABI。结果观察组血清hs-CRP比对照组明显升高(P<0.01),观察组ABI比对照组明显降低(P<0.05)。在观察组患者中,气阴两虚、肾阳亏虚、阴阳两虚与阴虚热盛患者血清hs-CRP,ABI均有明显差异(P<0.05,P<0.01);气阴两虚、肾阳亏虚之间的hs-CRP,ABI无明显差异(P>0.05);气阴两虚与阴阳两虚之间hs-CRP、ABI有明显差异(P<0.05);肾阳亏虚与阴阳两虚之间hs-CRP,ABI无明显差异(P>0.05)。结论血清hs-CRP和ABI可以指导糖尿病肾病患者的中医分型。

Objective To study the correlation between TCM types and high-sensitivity C-reactive protein （ hs-CRP ） , ankle-brachial index （ ABI） in patients with diabetic nephropathy .Methods 118 patients with diabetic nephropathy in Chinese tradition medicine type were enrolled into the observation group and 40 healthy people were enrolled into the control group .Serum hs-CRP and ABI were compared . Results Serum hs-CRP in the observation group was higher than that in the control group （ P〈0.01 ） .ABI in the observation group was lower than that in the control group （ P〈0.05 ） .There were significant differences in patients of yin deficiency and heat intensity , both deficiency of qi and yin, kidney yang deficiency , both deficiency of yin and yang about hs-CRP and ABI （P〈0.05,P〈0.01）.There wasn’ t significant difference between both deficiency of qi and yin , and kidney yang deficiency about hs-CRP and ABI （ P〉0.05 ） .There was significant difference between both deficiency of qi and yin , and both deficiency of yin and yang （ P 〈0.05 ） .There wasn ’ t significant difference between kidney yang deficiency , and both deficiency of yin and yang （ P〉0.05 ） .Conclusions Hs-CRP and ABI can instruct TCM type in patients with diabetic nephropathy .