脾氨肽在小儿支气管哮喘治疗中对免疫功能的影响分析

Influence of spleen aminopeptidase on immune function in the treatment of children with bronchial asthma

目的通过小儿支气管哮喘治疗中辅助使用脾氨肽的效果对比,研究脾氨肽在小儿支气管哮喘中对免疫功能的影响。方法将感染因素导致的小儿支气管哮喘是否使用脾氨肽分为治疗组和对照组,进行治疗有效率和T细胞亚群,IgE变化对比分析。结果感染因素中治疗组总有效率84.0%,对照组总有效率41.2%;治疗后患儿CD+4,CD+8,CD+4/CD+8比值均明显升高,IgE下降明显,治疗前后对比差异有统计学意义。结论感染因素支气管哮喘治疗中使用脾氨肽效果明显,患儿的免疫功能得到明显改善。

Objective To study the influence of spleen aminopeptidase on immune function in the treatment of children with bronchial asthma. Methods The children were divided into the treatment group and the control group based on the use of spleen aminopeptide. Their efficiency, T cell subsets, and IgE changes were comparatively analyzed. Results The total effective rate was 84% in the treatment group, and 41. 2% in the control group. After the treatment, CD4＋, CD8＋, CD4＋ /CD8＋ ratios increased significantly, and IgE decreased significantly with statistical significance. Conclusion Spleen aminopeptide is effective in the treatment of children with bronchial asthma, which can improve their immune function obviously.