骨折断端间注射富血小板血浆(PRP)治疗胫骨骨折不愈合的临床疗效观察

The Clinical Effection of Platelet-Rich Plasma(PRP)Injection Between Tibial Fracture Ends

目的探讨骨折断端间注射富血小板血浆（PRP）治疗胫骨骨折术后骨折不愈合的临床疗效。方法将11例胫骨骨折内固定术后骨折不愈合,同意使用PRP注射的患者列为实验组;将不同意使用PRP骨折断端注射的9例患者列为对照组。每月复查X线。复查随访3∽6个月。结果注射PRP组随访至6个月时X线片示骨折完全愈合4例,骨痂生长增多5例,2例患者无改变,有效率81.82%。对照组随访至6个月时X线片示骨折完全愈合1例,骨痂生长增多2例,6例患者骨折断端无改变,有效率33.33%。结论骨折断端间注射PRP能够有效促进骨折断端的修复,加快新骨形成,同时提高新生骨质量。

ObjectiveTo study the clinical effection of platelet rich plasma （PRP） injection between tibial fracture end.Methods 11 cases of tibial fracture internal fixation of fracture nonunion, agreed to the use of PRP injection as experimental group, patients will not agree to use the PRP of fracture end injection of 9 patients as control group, a monthly review of X-ray review 3 to 6 months of follow-up.Results The injection of the PRP group at the time of 6 months follow-up X line piece fracture healed completely in 4 cases, callus growth markedly increased in 5 cases, 2 case of patients with no change, the effective rate was 81.82%. Control group at the time of 6 months follow-up X line piece fracture healed completely in 1 cases, callus growth markedly increased in 2 cases, 6 cases of fracture end without change, the effective rate was 33.33%.Conclusion The PRP injection between the fracture end can effectively promote the bone defect repair, accelerate the new bone formation, at the same time improve the quality of new bone.