天智颗粒联合奥拉西坦对急性脑梗死后认知功能障碍的疗效观察

Effective observation on treating cognitive functional disorder caused by acute cerebral infarction with the Tianzhi granule plus oxiracetam

目的:观察天智颗粒治疗急性脑梗死后认知功能障碍的临床疗效。方法:将100例急性脑梗死后认知功能障碍患者随机分为治疗组和对照组,对照组口服奥拉西坦胶囊,治疗组口服天智颗粒和奥拉西坦胶囊,两组均连续治疗1个月,治疗前后分别采用简易精神状态量表(MME-E)及日常生活活动能力量表(ADL)对患者疗效进行评价。结果:天智颗粒和奥拉西坦联合组治疗急性脑梗死后认知障碍较奥拉西坦组改善明显,与对照组比较有统计学差异(P<0.05),且未见明显副作用。结论:天智颗粒联合奥拉西坦胶囊能较好的改善急性脑梗死后认知障碍,方法简便易行。

Objective： To observe clinical efficacy of the Tianzhi granule plus oxiracetam on cognitive functional disorder caused by acute cerebral infarction. Methods： 100 patients were randomly divided into the treatment group and the control group. The control group was given oxiracetam orally; another group was given the Tianzhi granule plus oxiracetam orally. Two groups received one month treatment. Clinical efficacy in two groups was evaluated based on MME-E and ADL. Results： The Tianzhi granule plus oxiracetam can obvious improve clinical symptoms. The difference was statistically significant （P〈0.05）. Conclusion： The Tianzhi granule plus oxiracetam showed good clinical effects and was easy to operate.