慢性肾衰竭氮质血症期实施中西结合疗法的临床研究

Clinical Study of Integrated Treatment of Traditional Chinese Medicine and Western Medicine during the Azotemia Course of Chronic Renal Failure

目的:研究慢性肾衰竭氮质血症期实施中西结合疗法的临床疗效。方法:参照组在基线治疗基础上应用α酮酸进行治疗,临床组在基线治疗基础上应用自拟固元健肾散进行治疗。两组均以30d为1个疗程。疗程结束后比照两组疗效及主要肾功指标治疗前后的变化情况。结果:临床组总有效率为86.36%,显著高于参照组的61.90%(P<0.05)。两组治疗前血尿素氮、血清肌酐及24h尿蛋白无显著差异(P>0.05),治疗后血尿素氮、血清肌酐及24h尿蛋白均显著下降(P<0.05),临床组下降幅度显著优于参照组(P<0.05)。结论:慢性肾衰竭氮质血症期实施中西结合疗法效果显著,可有效改善肾功能。

Objective： To study the clinical curative efficacy of integrated treatment of Traditional Chinese Medicine and western medicine during the azotemia course of chronic renal failure. Method： Both control group and control group received baseline treatment. Besides base treatment, the control group was given α -Keto Acid and the clinical group was given Powder for Reinforcing Primordial Qi and Kidney. Both the two groups took 30 days as one course. After the course, the curative efficacy and renal function of the two group before and after the treatment were contrasted with each other. Result： The total effective rate of clinical group was 86.36% which was significantly higher than that（61.90%） of the control group（P＜0.05）. Before the treatment, there were no significant differences in the blood urea nitrogen, serum creatinine and 24 hours volume of urine protein between the two groups （P＞0.05）. After the treatment, in the two groups, the blood urea nitrogen, serum creatinine and 24 hours volume of urine protein significantly reduced （P＜0.05）. The clinical group reduced more significantly than the control group （P＜0.05）. Conclusion： Integrated treatment of Traditional Chinese Medicine and western medicine during the azotemia course of chronic renal failure has significant effect. It can effectively improve the renal function.