某妇幼专科医院儿科常用剂型药品说明书调查分析

Investigation and Analysis of Drug Instructions of Commonly Used Dosage Form in Pediatrics of a Hospital Specializing in Maternal and Child Care

目的:了解儿童常用剂型药品说明书中儿童用药相关内容是否完整和全面。方法:横断面调查该院门诊儿科处方常用药品的说明书,分别就口服剂型、注射剂型、吸入剂型说明书中儿童用法用量、注意事项、禁忌、儿童用药项目,进行数据分析。结果:共调查439份药品说明书,口服剂型中用法用量按年龄段比例较高,有儿童用药内容项内容比例较低;注射剂型在用法用量按体重和有儿童用药项内容比例均较高,用法用量年龄段比例较低;吸入剂型用法用量按年龄段和注意事项项提及儿童用药内容比例较高。结论:妇幼专科医院儿科常用剂型说明书并非都有儿童相关内容,需积极倡导儿童临床试验以完善基础数据,加强临床药师工作以保证儿童用药安全。

Objective：To investigate the completeness of contents related to children medication in drug instructions of commonly used dosage form for children. Method：A cross-sectional survey of drug instructions of commonly used dosage form in pediatrics was done in the hospital. The data about usage, dosage, notes, contraindications for children in drug instructions of oral, injection and inhaled dosage form were analyzed. Result：In the 439 pieces of drug instructions investigated, for oral dosage form, usage and dosage given in accordance with age hold a higher proportion, while instructions with child medication item hold a lower proportion. For injections, both usage and dosage given in accordance with weight and instructions with child medication item hold a higher proportion, but usage and dosage given in accordance with age hold a lower proportion. For inhaled dosage form, usage and dosage given in accordance with age hold a higher proportion. Notes containing contents related to child medication also hold a higher proportion. Conclusion：Not all drug instructions of commonly used dosage form for children in hospital specializing in maternal and child care had contents related to child medication. Clinical experiment should be advocated to improve the basic data. Clinical work of pharmacists should be reinforced to ensure the security of children medication.