不同温度的桑通液雾化治疗对慢性阻塞性肺疾病急性加重期患者依从性的影响

Effect of Sangtong Spray with different temperature on the compliance of patients with acute exacerbation of chronic obstructive pulmonary disease

目的观察不同温度的桑通雾化液对慢性阻塞性肺疾病急性加重期（AECOPD）患者依从性的影响。方法将107例AECOPD患者随机分为3组,即对照组（35例）、治疗1组（36例）和治疗2组（36例）。3组均在常规用药基础上联合不同温度的桑通雾化液（对照组22~25℃,治疗1组43~45℃,治疗2组34~36℃）治疗,观察3组治疗前后临床症状及体征评分、呼吸频次、指脉氧及依从性的变化。结果治疗1组、治疗2组治疗后临床症状及体征均较本组治疗前改善（P〈0.01）,与对照组比较差异均有统计学意义（P〈0.05）;治疗1、2组治疗后舒适度及依从性改善（P〈0.01）,与对照组比较差异有均统计学意义（P〈0.05）。结论桑通雾化液加温后雾化能改善AECOPD患者临床症状及体征,降低呼吸频率,提高血氧饱和度,使患者感觉舒适,依从性好,有利于AECOPD患者的恢复。

Objective To investigate the effect of Sangtong Spray with different temperature on the compliance of patients with acute exacerbation of chronic obstructive pulmonary disease （AECOPD）. Methods 107 AE- COPD patients were randomly divided into three groups, the blank control group, treatment group 1 and treatment group 2. The three groups were all given the routine general treatment, combined with Sangtong Spray with different temperature. The clinical symptoms and signs, respiratory frequency, change of pulse oxygen, compliance of the three groups was observed before and after treatment. Results The clinical symptoms and signs in treatment group 1 and treatment group 2 improved significantly after treatment （P 〈 0.01 ）, compared with the control group there was signif- icant difference （ P 〈 0.05 ） ; After treatment, the respiratory rate, pulse oxygen and the compliance of patients can be improved （ P 〈 0.01 ）, compared with the control group （ P 〈 0.05 ）. Conclusion Sangtong Spray could significantly improve the patient＇s symptoms and signs, reduce respiratory rate, improve the blood oxygen saturation, making the patient feel comfortable, good compliances beneficial to the recovery of patients with AECOPD.