肥胖1号方治疗脾虚痰湿型肥胖症合并胰岛素抵抗疗效观察

Clinical effect observation of Feipang Yihao decoction on the treatment of spleen- deficiency and phlegmturbid stagnation type obesity with insulin resistance

目的观察肥胖1号方治疗脾虚痰湿型肥胖症合并胰岛素抵抗的临床疗效。方法将60例脾虚痰湿型肥胖症合并胰岛素抵抗患者随机分为2组,对照组30例予二甲双胍治疗,治疗组30例在对照组治疗基础上加肥胖1号方。2组均治疗12周后,统计2组治疗前后体质量指数(BMI)、胰岛素抵抗指数(HOMA-IR)及血脂变化。结果 2组治疗后BMI、HOMA-IR及血脂均较对照组明显改善(P<0.05)。结论肥胖1号方治疗脾虚痰湿型肥胖症合并胰岛素抵抗疗效确切,安全可靠。

Objective To survey the clinical effect of Feipang Yihao decoction on the treatment of spleen - deficiency and phlegm - turbid stagnation type obesity with insulin resistance Methods 60 cases of spleen - defi- ciency and phlegm - turbid stagnation type obesity with insulin resistance were randomly divided into a treatment group （ treated with Feipang - Yihao Decoction and Metformin） and a control group （ treated with Metformin） ,with 30 cases in each group and performed a therapeutic course for 12 weeks. The clinical efficacy and the change of symptom checklist and BMI,Blood lipid level and HOMA - IR before and after treatment were evaluated. Results After 12 weeks of treatment, BMI, Blood lipid level and HOMA - IR after treatment were obviously improved （P 〈 0.05 ） as compared with those before treatment in two groups （P 〈0.05 ）. Conclusion Feipang Yihao decoction on spleen - deficiency and phlegm -turbid stagnation type obesity with insulin resistance has safe and reliable curative effect.