妊娠期糖尿病患者血糖、血脂水平与新生儿体质量的关系

Relationship between blood lipid levels and blood glucose,body weight of pregnancy in gestational diabetes

目的:对妊娠期糖尿病(GDM)孕妇孕期血糖、血脂水平进行分析,探讨GDM孕妇血糖、血脂水平对新生儿出生体质量的影响。方法:空腹12h后,清晨采GDM孕妇肘静脉血测量血糖、血脂,另选择同期正常足月产妇95例作为对照组,对比观察两组血糖、血脂水平和孕期体质量增长值。结果:GDM组空腹血糖、血清总胆固醇(TC)、甘油三脂(TG)、孕期体质量增长值显著高于对照组(P<0.05),GDM组巨大儿比例高于对照组(P<0.05),而低密度脂蛋白(LDL)、高密度脂蛋白(HDL)水平差异无统计学意义(P>0.05)。结论:GDM组孕妇血糖、血脂水平与孕期体质量增长值、新生儿体质量呈正相关性,应对GDM孕妇进行饮食指导和血糖、血脂监测,有效控制血糖、血脂水平,降低巨大儿发生率。

Objective：To explore serum lipid level and blood glucose of gestational diabetes mellitus（GDM）pregnancy women on neonatal birth weight.Methods：12hours after fasting,ulnar vein blood was collected early morning to measure blood glucose,blood lipid.Another 95 normal pregnancy cases were selected as control group.Blood glucose,blood lipid and maternal body mass growth value were compared between the two groups.Results：Total cholesterol in GDM group,serum fasting blood glucose,TC,TG,maternal body mass growth were significantly higher than those of the control group（P〈0.05）;in GDM group the ratio of fetal macrosomia was higher than that of control group（P〈0.05）,and there was no significant difference in LDL,HDL levels between two groups（P〉0.05）.Conclusion：The levels of lipid and blood glucose,the growth of body weight of GDM pregnancy women are positively correlated with and body mass of pregnancy women and neonatal body mass.The diet should be guided,and blood glucose,blood lipid should be monitored to effectively control blood glucose and blood fat,reduce the incidence of macrosomia.