脑梗死患者血浆D-二聚体检测及临床价值

Clinical value of plasma D-dimer testing in patients with cerebral infarction

目的:研究血浆D-二聚体在脑梗死患者病情评估及预后评价中的临床应用价值。方法:以87例脑梗死患者为研究对象,比较不同病因及不同梗死灶大小脑梗死患者D-二聚体的变化。结果:心源性、非心源性及原因不明性脑梗死3组入院时D-二聚体、SSS评分均以心源性脑梗死较高,组间差异有统计学意义(P<0.05);治疗14d后3组D-二聚体、SSS评分均有改善,与入院比较差异有统计学意义(P<0.05)。3组治疗有效率比较无统计学差异(P>0.05)。3组不同梗死灶大小脑梗死患者各时间段D-二聚体比较,均以大梗死灶组D-二聚体血浆水平较高;3组D-二聚体血浆水平在治疗过程中均出现先上升后降低态势,3组第7天D-二聚体血浆水平均达到峰值。结论:D-二聚体对脑梗死的早期诊断、病情评估、疾病监测均有重要的意义。

Objective： To study the clinical value of plasma D- dimer value in assessing the condition and prognosis of patients with cerebral infarction. Methods.. A total of 87 cases of cerebral infarction were selected. D- dimer of patients with different causes and different cerebral infarct size were observed and compared. Results.. D- dimer and SSS scores of cardiac infarction patients were the highest, with significant difference among groups（P 〈0.05）. 14 d after treatment, El- dimer and SSS scores were significantly improved in three groups （P 〈 0.05） , there was no significant difference among groups （P〉 0.05）. D- dimer of large cerebral infarct size was the highest. During treatment, D- dimmer was increased firstly, then decreased. The peak was reached on the 7th d. Conclusion： D- dimmer is valuable in-early diagnosis of cerebral infarction, condition assessment and disease surveillance.