福州市口腔扁平苔藓和口腔白斑患者口腔念珠菌的驻菌情况分析

Analysis on the Presence of Oral Candida in Patients with Oral Lichen Planus and Oral Leukoplakia in Fuzhou City

目的:通过检测口腔扁平苔藓(OLP)患者和口腔白斑(OK)患者口腔念珠菌的驻菌情况,探讨念珠菌与口腔扁平苔藓和口腔白斑发病的相关性。方法:选取福建省立医院口腔科的扁平苔藓(OLP)、白斑(OK)患者及健康人各25例,取其口腔含漱液,采用CHRO Magar Candida假丝酵母菌显色培养基进行分离鉴定,观察并比较三组念珠菌的检出率。结果:健康对照组、扁平苔藓组及白斑患者组念珠菌的检出率分别为36.00%、40.00%和36.00%,三组比较差异无统计学意义(P>0.05);其中白色念珠菌检出率分别为健康对照组20.00%、扁平苔藓组24.00%及白斑患者组24.00%,热带念珠菌的检出率分别为8.00%、12.00%和8.00%,光滑念珠菌的检出率均为4.00%,三组受检者口腔内各菌群检出率比较差异均无统计学意义(P>0.05)。结论:念珠菌与口腔扁平苔藓和口腔白斑发病无显著相关性。

Objective：To investigate the correlation of candida with oral lichen planus（OLP） and oral leukoplakia（OLK） through detecting the oral candida in patients with OLP and OLK.Method：A total of 25 OLP patients,25 OLK patients and 25 healthy individuals were selected from the department of stomatology in Fujian Provincial Hospital.The oral rinse liquid of all the subjects were collected,followed by separation and identification using CHRO Magar Candida to observe and compare the candida detection rates of the three groups.Result：The candida detection rates of the control group,OLP group and OLK group were 36.00%,40.00% and 36.00%,and the differences among three groups were not statistically significant（P〉0.05）.The Candida albicans detection rates of the control group,OLP group and OLK group were 20.00%,24.00% and 24.00%,the Candida tropicalis detection rates were 8.00%,12.00% and 8.00%.The Candida glabrata detection rates of three groups were all 4.00%,and the oral detection rates of each kind of candida in three groups showed no statistically significant difference（P〉0.05）.Conclusion：The presence of candida is not significantly correlated with the onset of OLP and OLK.