类风湿关节炎继发糖尿病患者肺部感染的临床治疗效果观察

Study on clinical treatment effects on pulmonary infections in patients with diabetes secondary to rheumatoid arthritis

目的探讨胰岛素联合抗菌药物治疗类风湿关节炎继发糖尿病患者肺部感染的临床效果,为临床治疗提供参考依据。方法选择2007年3月-2012年12月医院收治的80例类风湿关节炎继发糖尿病患者发生肺感染的临床资料,将其分为观察组和对照组,每组各40例,观察组患者采用胰岛素联合抗菌药物进行治疗,对照组患者使用口服降糖药联合抗菌药物进行治疗,比较两组患者的治疗效果,数据采用SPSS 17.0统计软件进行分析。结果观察组患者的血糖达标时间及住院时间分别为(4.3±0.5)d、(8.0±2.1)d,均明显优于对照组患者,且差异有统计学意义(P<0.05),而且观察组患者的总有效率为100.0%,明显高于对照组患者的85.0%,差异有统计学意义(P<0.05)。结论胰岛素联合抗菌药物治疗类风湿关节炎继发糖尿病并发肺感染患者疗效显著,有效缩短住院时间节省费用,值得临床广泛应用。

OBJECTIVE To discuss the clinical effects of insulin combined antibiotic therapy for pulmonary infections in patients with diabetes secondary to rheumatoid arthritis,and to provide support for clinical treatment.METHODS Clinical data of 80 patients admitted to hospital suffering from the diseases as aforementioned in Mar.2007 to Dec.2012 were selected.They were divided into the observation group and the control group randomly,40 cases in each group.The patients in the observation group were treated with insulin combined antimicrobial treatment,the other group with oral hypoglycemic agent combined antimicrobial treatment.Clinical effects of groups were compared,and the data were analyzed using SPSS 17.0statistical software.RESULTS The time to normal blood glucose（4.3±0.5）d and the average hospitalized days（8.0±2.1）d in the observation group were significantly less than the patients in control group（P〈0.05）.Total effective rate in the observation group was significantly higher than that in the control group（100.0% vs 85.0%,P〈0.05）.CONCLUSIONS Therapy of insulin combined antibiotics for pulmonary infection in patients with diabetes secondary to rheumatoid arthritis has a more significant effect,which can shorten the hospitalized time and reduce cost of the patients.