H_6P_2W_(18)O_(62)/SiO_2催化合成环己酮1,2-丙二醇缩酮

Catalytic synthesis of cyclohexanone 1,2- propanediol ketal by H_6P_2W_(18)O_(62)/SiO_2

以二氧化硅负载Dawson型磷钨酸H6P2W18O62/SiO2为催化剂,采用环己酮和1,2-丙二醇为原料合成环己酮1,2-丙二醇缩酮.探讨H6P2W18O62/SiO2对缩酮反应的催化活性,较系统地研究了各种因素对产物收率的影响.实验表明:H6P2W18O62/SiO2是合成环己酮1,2-丙二醇缩酮的良好催化剂,在n(环己酮)∶n(1,2-丙二醇)=1∶1.5,带水剂环己烷6 mL,催化剂用量占反应物料总质量的0.6%,反应时间60 min的优化条件下,环己酮1,2-丙二醇缩酮的收率可达85.4%.

Cyclohexanone 1,2-propanediol ketal was synthesized from cyclohexanone and 1,2-propanediol in the presence of H6 P2 W18 O62/SiO2 as catalyst.The factors influencing the synthesis were discussed and the best reaction conditions were found out .Experimental results showed that H 6 P2 W18 O62/SiO2 was an excellent catalyst .The optimum conditions are：molar ratio of cyclohexanone to 1,2-propanediol is 1∶1.5, the volume of cyclohexane as the water-carrying agent is 6 mL, the quantity of catalyst is equal to 0.6%of feed stocks , and the reaction time is 60 min.Under these conditions , the yield of cyclohexanone 1,2-propanediol ketal can reach 85.4 %.