金龙固本合剂对支气管哮喘缓解期的影响

Jinlong-Gubenmixturefor the treatment of asthma at the remission stage

目的：观察金龙固本合剂治疗支气管哮喘缓解期（宿痰伏肺证）患者的临床疗效。方法采用网络在线随机系统将108例支气管哮喘缓解期患者随机分为两组，治疗组48例口服金龙固本合剂治疗，对照组47例不进行药物干预，均观察3个月，随访1年。比较两组观察前后国际哮喘控制测试表评分（ACT）和第一秒用力呼气量（FEV1）变化。结果治疗组观察及随访期间ACT评分（t值分别为2.931、2.618）、FEV1（t 值分别为2.011、2.680）均较同组观察前明显改善（P＜0.05），且疗效优于对照组（P＜0.01）。观察3个月后，治疗组总有效率为93.75%（45/48），对照组为78.72%（37/47），两组总有效率比较，差异有统计学意义（U＝-0.4531，P＜0.01）。结论金龙固本合剂可有效改善支气管哮喘缓解期患者（宿痰伏肺证）临床症状、减少复发。

Objective To observe the effect of treating asthma in remission stage（Latent phlegm in lung syndrome） withJinlong-Gubenmixture.Methods 108 patients of asthma on remission stage were randomized into a control group and a treatment group. The treatment group was givenJinLong-GuBen mixture. The control group was given nothing for treatment. Both groups were treated for 120 days and follow-up period were 360 days. The change of ACT scores and FEV1 was observed.Results After treatment, ACT scores（t=2.931, 2.618） and FEV1（t=2.011, 2.680） of treatment groups were markedly increased than before the treatment（P〈0.05）, and the effect of the treatment group was better than the control group（P〈0.01）. After treatment, the effective rate of treatment group was 93.75%（45/48）, and the effective rate of control group was 78.72%（37/47）,there existed statistical significance between the two groups（U=-0.4531,P〈0.01）. Conclusion The theory of latent phlegm in lung has a good guiding function in treating asthma in remission stage（Latent phlegm in lung syndrome）.