烟台市成人社区获得性肺炎病毒病原学分类的研究

Etiological classification of virus in adult community-acquired pneumonia in Yantai

对128例确诊为社区获得性肺炎患者的咽拭子采用多重PCR方法进行病毒分类,分析病毒分类与年龄和季节的关系.病毒性肺炎占34.4％ （44/128）.44例病毒阳性患者中,甲型流感病毒占22.7％（10/44）,鼻病毒、腺病毒各占15.9％（各7/44）,副流感病毒1型和人偏肺病毒各占9.1％（各4/44）,乙型流感病毒占6.8％ （3/44）,副流感病毒2型、副流感病毒3型及肠道病毒各占2.3％（各1/44）,另有6例为多重病毒感染（13.6％）.病毒性肺炎在冬春季节发病高,发病人群中20～ 29岁所占比例高.在烟台市成人社区获得性肺炎病原构成中,病毒性肺炎所占比例较大,尤其以甲型流感病毒、鼻病毒和腺病毒为主.

To employ multiplex polymerase chain reaction （PCR） to classify the types of virus in 128 patients of community-acquired pneumonia and analyze the relationship between type of virus,age and seasons.The positive rate of viral pneumonia was 34.4% （44/128）.In 44 virus positive patients,the rates of influenza A virus,rhinovirus,adenovirus,parainfluenza type 1,human metapneumovirus virus,influenza B virus,parainfluenza type 2,parainfluenza type 3 and enterovirus were 22.7% （10/44）,15.9% （7/44）,15.9% （7/44）,9.1% （4/44）,9.1% （4/44）6.8% （3/44）,2.3% （1/44）,2.3% （1/44） and 2.3% （1/44） respectively.And other 6（13.6%） patients were at least infected by one virus.The viral pneumonia had a high positive rate in spring and winter.And the age group of 20 to 29 years had a high positive rate.The major pathogen contributing to adult community-acquired pneumonia in Yantai were influenza A virus,rhinovirus and adenovirus.