中药结合急诊溶栓对急性心肌梗死患者血管再通率和并发症发生情况的影响

Effects of Emergency Thrombolytic Therapy Combined with Traditional Chinese Medicine on the Vascular Recanalization and Complications Rates of the Patients with Acute Myocardial Infarction

目的:观察和比较中药结合急诊溶栓对急性心肌梗死(AMI)患者血管再通率和并发症发生情况的影响。方法:选取120例AMI患者作为研究对象,将其随机分为观察组和对照组,每组各60例。对照组患者给予静脉点注尿激酶急诊溶栓联合口服阿司匹林治疗,观察组患者给予静脉点注尿激酶急诊溶栓联合中药治疗。对2组患者的血管再通率以及出血并发症和严重心梗并发症的发生情况进行观察和比较。结果:观察组和对照组患者的血管再通率分别为73.3%和50%,观察组显著高于对照组(P<0.05);对照组中1周内出现血管再闭塞的患者比例显著高于观察组(P<0.05),观察组中发生出血并发症的患者比例显著低于对照组(P<0.05),在观察组中发生休克、心力衰竭、心律失常等心梗并发症的患者比例均显著低于对照组(P均小于0.05)。结论:中药结合急诊溶栓治疗AMI可提高血管再通率、降低出血并发症和严重心梗并发症的发生率,对于改善患者预后具有积极意义。

Objective：To observe and compare the effects of emergency thrombolytic therapy combined with traditional Chinese medi-cine on the vascular recanalization and complications rates of the patients with acute myocardial infarction （AMI）.Methods：One hun-dred and twenty cases of AMI patients were selected as the research objects and randomly divided into the observation group （n =60） and the control group （n =60）.The patients in the control group were treated with intravenous infusion of urokinase thrombolysis thera-py combined with oral administration of aspirin,while the patients in the observation group were treated with intravenous infusion of uro-kinase thrombolysis therapy combined with traditional Chinese medicine.The vascular recanalization rates,the bleeding complications rates,and the severe myocardial infarction complications rates of the patients in the two groups were observed and compared.Results：The vascular recanalization rates of the patients in the observation group and the control group were 73.3% and 50% respectively.The rate of the observation group was significantly higher than that of the control group （P 〈0.05）;the rate of occluded vessels appearing at the 1st week after treatment of the control group was significantly higher than that of the observation group （P 〈0.05）.The proportion of the patients with the bleeding complications of the observation group was significantly lower than that of the control group （P 〈0.05）. The proportions of the patients with the severe myocardial infarction complications such as shock,heart failure,arrhythmia in the obser-vation group were significantly lower than those of the control group （P 〈0.05）.Conclusion：The application of emergency thrombolyt-ic therapy combined with traditional Chinese medicine in treatment of the patients with AMI can improve the recanalization rates,reduce the rates of the bleeding complications and severe myocardial infarction complications and has a positive significance for improving the prognosis of patients.