摘要
红光发射稀土上转换发光纳米晶(UCNPs)在光动力治疗(PDT)等方面具有特定的优势。将油溶性的UCNPs通过表面改性转变为水溶性,对其在生物医疗、疾病诊断等方面的应用具有重要意义。利用一种简单易行的方法将具有红光发射的UCNPs进行介孔直接功能化表面修饰,制备了一种具有良好水溶性的纳米材料NaYF4:Yb/Er/Mn@mSiO2。实验结果表明该材料核-壳结构明显,形貌均一,在980 nm的激发下保持了上转换发光特性。该材料在光动力治疗等方面具有良好的潜在应用价值。
Rare earth-upconverting nanoparticles (UCNPs) with red emission are bestowed with unique advantages in photodynamic therapy (PDT). If they can be modified from the oil-soluble to water-soluble, it will be of great significance in biological medical treatment and diagnosis. In this paper, we conducted directly mesoporous SiO2 coating onto the surface of UCNPs with red emission by using a simple and easy method. The obtained NaYF4 : Yb/ Er/Mn@ mSiO2 nanomaterials had obvious core-shell structure and uniform morphology. They could keep the up- conversion luminescent properties under the 980 nm excitation and had good water solubility. The modified core- shell nanomaterials had potential application in the field of PDT.
出处
《中国稀土学报》
CAS
CSCD
北大核心
2014年第5期534-540,共7页
Journal of the Chinese Society of Rare Earths
基金
国家自然科学基金项目(21001072
21231004
21201117)
上海市教育委员会科研创新项目(13ZZ073)
上海市科委项目(13NM1401100
13NM1401101)
上海市启明星计划(14QA1401800)
稀土资源利用国家重点实验室开放课题(RERU2014012)资助
关键词
稀土上转换发光
红光
纳米材料
介孔功能化
核-壳结构
rare earth upconversion luminescence
red emission
nanomaterials
meso-functionalization
core-shell structures