摘要
以二氧化碳(CO2)物理活化法制备了核桃壳活性炭,考察了活化温度、活化时间对核桃壳活性炭得率及烟酸吸附量的影响。以所制备的核桃壳活性炭为烟酸载体,在不同的释放介质(蒸馏水、人工胃液或人工肠液)中进行烟酸释放性能研究。结果表明,人工胃液和人工肠液能促进活性炭对烟酸的释放,其累计释放率分别达到43.96%和47.69%。核桃壳活性炭在3种不同介质中的不同释放阶段的释放过程均符合Higuchi模型。
Walnut-shell activated carbons(WSAC)were prepared by CO2 activation method.The effect of activation temperature,activation time on the yield of WSAC and adsorptive capacity of nicotinic acid were studied.Then WSAC were used as carrier of nicotinic acid and the process of releasing nicotinic acid were studied.The cumulative release rate of nicotinic acid in simulated gastric fluid(SGF)and simulated intestinal fluid(SIF)were 43.96%and 47.69%,respectively.Higuchi model was found to be suitable for describing the process of WSAC releasing nicotinic acid in different media.
出处
《化学与生物工程》
CAS
2014年第9期49-51,58,共4页
Chemistry & Bioengineering
基金
武汉工程大学重点教学建设工程项目(Z2011004)
武汉工程大学第九期大学生校长基金项目(2014001)
关键词
核桃壳活性炭
CO2活化
烟酸
缓释
Higuchi模型
walnut-shell activated carbon
CO2activation
nicotinic acid
sustained release
Higuchi model