原位新膀胱术后肾功能损害病因的探讨

The Etiology of Renal Function Injury after Orthotopic Neobladder Reconstruction

根治性膀胱全切伴淋巴结清扫术及尿流改道是治疗浸润性膀胱癌的金标准。而膀胱全切后膀胱重建和尿流改道方式的研究一直都是泌尿外科学者所面临的课题。原位新膀胱手术已成为国内外一些大型的医学中心最主流的尿流改道术式,但到目前为止还没有一种手术方式能够真正满意地代替膀胱的作用。在该术式的推广过程中,发现吻合口狭窄、尿潴留、尿路感染、代谢紊乱、术后肾功能损害等并发症的发生概率较高。

Radical cystectomy and lymphadenectomy and urinary diversion is the gold standard for the treatment of invasive bladder cancer.But after radical cystectomy and urinms diversion bladder reconstruction method is always the problem of urologists.Orthotopic neobladder operation has become the major urinmy diversion approach in some domestic and foreign large-scale medical centers,however so far no operation mode can truly satisfyingly replace the bladder function.In the promotion of the operative approach,higher probability of anastomotic stricture,urinary retention,urinary tract infection,metabolic disorders,postoperative renal dysfunction and other complications is found.