老年脑卒中患者上消化道出血与肺部感染的关系分析

Analysis on the Relationship between Upper Gastrointestinal Hemorrhage and Pulmonary Infection in Elderly Stroke Patients

目的探讨老年脑卒中患者上消化道出血(UGH)与肺部感染及其与脑卒中死亡的关系。方法选择2010年1月至2011年6月在北京老年医院卒中病房住院治疗的476例首发脑卒中患者,根据患者是否合并UGH分为UGH组和非UGH组。探讨UGH与肺部感染的关系,以及两者与脑卒中死亡的相关性。结果 UGH组患者发生肺部感染的情况显著高于非UGH组(χ2=29.179,P<0.001);脑卒中并发UGH的患者较未并发UGH者的病死率显著升高(χ2=33.719,P<0.001),脑卒中并发肺部感染的患者与未并发肺部感染者的病死率比较,差异有统计学意义(χ2=31.302,P<0.001);老年脑卒中患者并发UGH与并发肺部感染间存在正相关(r=0.24,P<0.001)。结论积极防治UGH可预防老年脑卒中患者肺部感染的发生,可达到降低老年脑卒中患者病死率、改善预后的目的。

Objective To investigate the relationship between upper gastrointestinal hemorrhage（UGH） and pulmonaU infection in elderly stroke patients.Methods A total of 476 cases of elderly patients with stroke admitted in Beijing Geriatric Hospital from Jan.2010 to Jun.2011 were selected and divided into UGH group and non-UGH group.The relationship between U GH and pulmonary infection,and their correlation with stroke mortality was explored.Results The incidence rate of pulmonary infection of UGH group was significant higher than non-UGH group（x2 =29.179,P 〈 0.001） and with higher stroke mortality rate（x2 =33.719,P 〈 0.001）.The difference of mortality rate between patients with pulmonary infection and without was statistically significant（x2 =31.302,P 〈 0.001）.The incidence of U GH was positively correlated with the incidence of pulmonmy infection in elderly stroke patient（r =0.24,P 〈 0.001）.Conclusion Prevention and cure of UGH can prevent the incidence of pulmonary infection among elderly stroke patients,so as to reduce the mortality and improve the prognosis.