鼠神经生长因子联合α-硫辛酸对糖尿病周围神经病变症状的影响被引量：2

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摘要目的观察鼠神经生长因子联合α-硫辛酸(ALA)对糖尿病周围神经病变(DPN)症状的影响。方法将68例糖尿病周围神经病变患者随机分为试验组和对照组各34例。两组均通过饮食、运动、口服降糖药和(或)注射胰岛素将血糖控制在正常范围,试验组予鼠神经生长因子针联合ALA治疗;对照组仅予ALA治疗。观察两组治疗前后的神经病变总症状评分(TSS)情况。结果两组TSS评分治疗后均较治疗前有明显下降,试验组下降幅度大于对照组,除灼热感外,余4项差异均有统计学意义。结论鼠神经生长因子针联合ALA治疗DPN,与单用ALA比较,两组均可改善DPN引起的肢体刺痛、灼热感、感觉减退、麻木症状,但前者对刺痛、感觉减退、麻木3项症状更有优势。

作者杨萍余海港

机构地区浙江绍兴第二医院内分泌科永嘉县瓯北城市新区医院内儿科

出处《中国乡村医药》 2014年第17期3-4,共2页

关键词鼠神经生长因子 α- 硫辛酸糖尿病周围神经病变症状

分类号 R587.2 [医药卫生—内分泌]

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参考文献5

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