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小剂量右美托咪定复合七氟醚诱导喉罩置入用于小儿下腹部手术的临床观察 被引量:8

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摘要 目的观察小剂量右美托咪定复合七氟醚诱导喉罩置入用于小儿下腹部手术麻醉的可行性和安全性,并与传统的单纯七氟醚诱导全麻比较。方法选择ASAⅠ-Ⅱ级下腹部手术患儿40例,随机分成右美托咪定组(M组)和传统单纯七氟醚诱导组(N组),每组20例。M组静脉泵注右美托咪定0.5μg/kg 10 min后行8%浓度的七氟醚吸入诱导(氧流量2-3 L/min),患儿入睡后置入喉罩,术中保留自主呼吸,以七氟醚和芬太尼维持麻醉;N组采用传统单纯七氟醚诱导,麻醉维持同前。结果 M组均顺利完成诱导和手术,N组2例因患儿屏气、剧烈呛咳麻醉诱导失败,后改静脉诱导完成手术;麻醉诱导时间、术中芬太尼的用量M组均小于N组;2组术中血压与给药前比较无明显变化,M组术中心率下降明显;术后M组有6例轻度烦躁,N组有11例烦躁,其中5例躁动评分4分以上,给予丙泊酚处理后缓解。结论小剂量右美托咪定复合七氟醚诱导喉罩置入用于小儿下腹部手术,有利于患儿在安静的状态接受麻醉诱导,且诱导更迅速,麻醉苏醒期患儿躁动比例明显降低,两者复合使用使患儿在整个围麻醉期更安静、舒适。
出处 《现代中西医结合杂志》 CAS 2014年第29期3274-3276,共3页 Modern Journal of Integrated Traditional Chinese and Western Medicine
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