氯丙嗪与硝普钠联合在主动脉夹层伴高血压患者治疗中的价值

Applications of chlorderazin and sodium nitroprusside in the treatment of patients with acute aortic dissection and hypertension

主动脉夹层（aortic dissection,AD）属心血管急危重症,误诊和漏诊率高达39%~60%,急性期死亡率在36%~71%,临床处理棘手[1]。本研究旨在观察静脉应用硝普钠控制AD伴高血压的基础上,加用盐酸氯丙嗪静脉应用后的临床价值。1对象与方法选择2007-05-2013-04在我院确诊的急性AD伴高血压,有或无高血压病史,入院后需要进一步降压治疗者32例。

Summary This study explored the efficacy of intravenous chlorderazin for patients with acute aortic dissec- tion and hypertension. We compared with hypertension control within 30 minutes, betaxolol daily dose, and appli- cation number of times of analgesic and antiemetic between Sodium Nitroprusside Group and Chlorderazin and So- dium Nitroprusside Group. The results showed that intravenous Chlorderazin combined with Sodium Nitroprusside was more suitable than intravenous Sodium Nitroprusside alone in the treatment of aortic dissection-related hyper- tension.