新疆墨玉县维吾尔族血糖异常分布与慢性肾脏病的流行病学调查

Survey on Pathoglycemia Distribution and Chronic Kidney Disease Among Uygur in Moyu Country in Xinjiang

目的：了解和田墨玉县农村维吾尔族成人居民血糖异常分布情况，分析血糖异常分布与慢性肾脏病（ CKD）的关系。方法：从“新疆墨玉县农村维吾尔族成人 CKD 流行病学调查”资料库中，获取资料完整的1552人用于分析。结果：和田墨玉县18岁以上居民空腹血糖（FPG）异常及糖尿病初患病率分别为27．51%（95% CI：27．47-27．85）和4．19%（95%CI：3．19-5．18），年龄、性别标化率：27．66%（95% CI：27．47-27．85）和4．35%（95% CI：4．27-4．44），FPG 异常及糖尿病患病率随年龄增长而升高（ P ﹤0．05）。FPG 正常组，FPG 异常组和糖尿病组的白蛋白尿和 CKD 患病率分别为（3．30%，5．85%，10．77% vs 3．96%，7．03%，12．31%），且随 FPG 水平增高而升高（P ﹤0．01）。FPG 异常合并高血压或高三酰甘油血症时，CKD 患病率相应增高。结论：血糖分布异常和 CKD 相关，关注糖尿病的同时，应重视 FPG 异常并控制高血压，高三酰甘油血症等因素。

Objective：To investigate the distribution status of pathoglycemia among Uygur adults in Moyu country and its re-lationship with chronic kidney disease（CKD）was evaluated. Methods：Data were obtained from the database of“the survey of chron-ic kidney diseases among Uygur adults in Xinjiang”,the final samples consisted of 1552 persons. Results：The crude prevalence of pathoglycemia and diabetes among Uygur adults were 27. 51%（95% CI：27. 47 - 27. 85）vs 4. 19%（95% CI：3. 19 - 5. 18）respec-tively,after adjusted for age and sex,the adjusted incidence rates were 27. 66%（95% CI：27. 47 - 27. 85）and 4. 35%（95% CI：4. 27 - 4. 44）,the prevalence of pathoglycemia and diabetes with no sex difference and increasing prevalence with increasing age（P ﹤0. 05）. The prevalence of albuminuria and CKD in normal FPG,pathoglycemia or diabetes were 3. 30% ,5. 85% ,10. 77% vs 3. 96% ,7. 03% ,12. 31% respectively,and the incidence was increased with age（P ﹤ 0. 05）. What’s more the prevalence of albu-minuria and CKD were significantly higher in the pathoglycemia with hypertension（P ﹤ 0. 05）and the prevalence of CKD were signifi-cantly higher in the pathoglycemia with elevated triglyceride（P ﹤ 0. 05）. Conclusion：The incidence of CKD was correlated with pathoglycemia. People should take care of FPG but not to lose the focus on associated risk factors such as blood pressure and elevated triglyceride.