磁共振磁化传递对比技术在脑内微小转移瘤中的应用

Diagnostic value of magnetic transfer contrast in intracranial metastasis

目的探讨磁共振磁化传递对比(MTC)技术对脑内微小转移瘤的应用价值。方法对37例患有脑转移瘤的病人行常规扫描后再行T_1-FLAIR和SE序列的T_1WI加MTC技术增强扫描,分别统计增强后T_1-FLAIR和T_1WI+MTC序列显示转移瘤的数目、大小、位置等,并比较2种序列图像的病灶-背景的对比度/噪声(C/Ns)值。结果 37例患者中,共计135个病灶,T_1WI+MTC显示133个病灶,显示率为98.5%,T_1-FLAIR序列显示129病灶,显示率为95.6%。T_1WI+MTC序列图像病灶-背景的C/Ns值为28.95±6.43,T_1-FLAIR序列图像病灶-背景的C/Ns值为14.45±7.64,T_1WI+MTC序列的C/Ns值高于T_1-FLAIR序列的C/Ns值(t=7.06,P<0.01)。结论在显示脑内微小转移瘤方面,增强T_1WI+MTC序列比T_1-FLAIR序列更为敏感,MTC技术对评估脑内转移瘤具有重要的临床意义。

Objective To investigate the value of magnetic transfer contrast（MTC）in demonstrating intracranial metastasis. Methods 37 patients with intracranial metastases underwent MRI including contrast-enhanced T1-FLAIR and T1-weighted sequence with MTC（T1＋MTC）.The number,size,location,and contrast-to-noise ratio（CNR）of the metastases on T1-FLAIR and T1＋MTC images were compared.Results Of 135 metastatic lesions,T1＋MTC images showed significantly（t=7.06,P〈0.01）more lesions （133,98.5%）with higher CNR（28.95±6.43）than T1-FLAIR（129,95.6%,14.45±7.64）.Conclusion T1＋MTC is more sensitive than T1-FLAIR in demonstrating intracranial metastasis.