米氮平口腔崩解片治疗抑郁症患者的临床研究概述

Clinical applications of mirtazapine orally disintegrating tablets in depression treatment

除了研发新药以外,现有药物新剂型的研发和应用也是治疗抑郁症的新思路。口崩剂型抗抑郁药米氮平口腔崩解片凭借其便于携带、口感良好及易于吞服等优点,作为能较好改善抑郁症患者依从性的一种剂型在临床广泛应用。本文从疾病本身的特点,结合抗抑郁药物的药理特征和不良反应,介绍米氮平口腔崩解片在抑郁症患者的临床研究情况。

Besides developing new agents, the development and application of new formulation of present available agents is a new concept to treat depression. With the advantages of portability, good taste and easy swallowing, mirtazapine orally disintegrating tablets （ODT） is one kind of formulations widely used in clinic to improve the patient compliance. From the points of disease characteristics combined with the pharmacological activity and adverse reactions of antidepressant drugs, the paper reviewed the clinical applications of mirtazapine ODT in the depression treatment.