超声引导介入治疗首发和术后复发卵巢子宫内膜异位囊肿疗效比较

Effect of ultrasound-guided interventional treatment in the first-episode and recurrence ovarian endometrioma

目的比较超声引导介入治疗首发和术后复发卵巢子宫内膜异位囊肿疗效。方法收集卵巢子宫内膜异位囊肿患者275例,首发组122例、复发组153例。对两组患者行超声引导下经腹或经阴道穿刺抽吸囊液后注入无水乙醇硬化治疗,术后随访12个月,比较两组痛经和下腹部疼痛复发率,以及囊肿治愈率、显效率、次显效率和无效率。结果治疗即刻两组囊肿均完全消失;119例患者(146个囊肿,首发组60个,复发组86个)完成随访,随访12个月,两组患者痛经及下腹部疼痛复发率差异无统计学意义(P均>0.05);首发组囊肿治愈率68.33%(41/60)、显效率5.00%(3/60)、次显效率13.33%(8/60)、无效率13.33%(8/60),复发组囊肿治愈率62.79%(54/86)、显效率2.33%(2/86)、次显效率6.78%(6/86)、无效率27.91%(24/86),两组囊肿无效率差异有统计学意义(P<0.05),治愈率、显效率、次显效率差异均无统计学意义(P均>0.05)。结论超声引导介入治疗首发卵巢子宫内膜异位囊肿疗效优于复发卵巢子宫内膜异位囊肿。

Objective To compare the effect of ultrasound-guided interventional treatment in the first-episode and recurrence ovarian endometrioma.Methods Totally 275 patients of ovarian endometrioma received ultrasound-guided transabdominal or transvaginal injection of ethanol dehydration,among them,there were 122first-episode patients（first-episode group）and 153 recurrence patients（recurrence group）.All the patients were followed-up for 6—12months after interventional treatment.The recurrence rate of dysmenorrhea and pelvic pain,the cure rate,markedly efficiency rate,the second efficiency rate and inefficiency rate of the two groups were compared.Results Cysts of the two groups were both completely disappeared instantly after interventional treatment.There were 119patients（146cystis,including 60 cystics in first-episode group and 86 cystics in recurrence group）completed the follow-up.At follow-up of 12 months,the recurrence rate of dysmenorrhea and pelvic pain were not statistically difference（both P〈0.05）between the two groups.The inefficiency rate of the first-episode group was 13.33%（8/60）,which was significantly lower than that of recurrence group（27.91% [24/86],P〈0.05）.The cure rate,markedly efficiency rate and second efficiency rate was 68.33%（41/60）,5.00%（3/60）and 13.33%（8/60）in first-episode group,and 62.79%（54/86）,2.33%（2/86）,and 6.78%（6/86）in recurrence group,with no statistical differences（all P〈0.05）.Conclusion Ultrasound-guided interventional treatment of ovarian endometrioma is more effective for the first-episode patients compared with the recurrence patients.