蒙脱石散联合头孢噻肟钠治疗小儿细菌性腹泻106例临床观察

The clinical observation of montmorillonite powder and cefotaxime sodium in treatment of 106 cases children with bacterial diarrhea

目的：探讨蒙脱石散联合头孢噻肟钠治疗小儿细菌性腹泻的临床应用价值，为临床推广作出指导。方法选择我院2011年2月-2013年2月收治的186例细菌性腹泻患儿为研究对象，将其随机分为两组。对照组患儿在常规对症支持治疗基础上给予口服蒙脱石散治疗，观察组患儿则在对照组的基础上再给予头孢噻肟钠静脉滴注治疗，观察两组患者治疗后的临床治疗效果以及不良反应情况。结果观察组患儿治疗后的优良率为99.06%，明显高于对照组86.25%，差异具有统计学意义（P〈0.05）；观察组患儿治疗后各项指标均明显优于对照组，差异具有统计学意义（P〈0.05）；两组患儿治疗后均未出现明显严重不良反应。结论蒙脱石散联合头孢噻肟钠治疗小儿细菌性腹泻效果显著，且安全可靠，值得在临床上广泛推广。

Objective To investigate clinical application value of montmorillonite powder and cefotaxime sodium in the treatment of children with bacterial diarrhea, which made guidance for clinical treatment. Methods A total of 186 cases patients admitted to our hospital from February 2011 to February 2013 were divided into control group （treated with montmorillonite powder based on general symptomatic and supportive treatment） and observation group （treated with ce-fotaxime sodium based on control group）, the clinical effects and adverse reactions of two groups were compared after treatment. Results The excellent and good rate of observation group （99.06%） was higher than that of control group （86.25%）, the difference was statistically significant （P〈0.05）;The indicators of observation group were better than that of control group,the difference was statistically significant （P〈0.05）;Both of two groups had no serious adverse reactions. Conclusion Montmorillonite powder and cefotaxime sodium has significant effects on treating bacterial diarrhea in chil-dren, it is worthy of clinical widespread use.