电针治疗T2DM伴肥胖203例研究

Electro-acupuncture Treatment on 203 Cases for T2MD with Obesity

观察电针治疗2型糖尿(T2DM)病肥胖患者的疗效。方法:电针治疗203例T2DM伴肥胖患者。观察治疗3个月前后患者空腹血糖(FBS)、空腹胰岛素(FINS)、胰岛素敏感指数(ISI)、胰岛素抵抗指数(Homa-IR)、胰岛素分泌指数(Homa-β)、肥胖度(A)、体质量(Kg)、体质指数(BMI)和体脂百分率(F%)的变化,观察肥胖和证型对电针降糖疗效的影响。结果:与治疗前相比,203例患者经治疗后,FINS、HomaIR、FBS都有显著回降(P<0.01),ISI、Homa-β显著回升(P<0.01),治疗前后比较胰岛β细胞功能改善均有显著统计学意义;A、体质量、BMI、F%均显著下降(P<0.01)。肥胖能影响电针加耳针降糖疗效,证型无影响。结论:电针能显著纠正T2DM伴肥胖患者的血糖,保护胰岛β细胞功能,并且能降低患者体质量。

This study was aimed to observe the effect of electro-acupuncture （EA） treatment on Zhong-Xiao （ZX, T2MD） with obesity. A total of 203 patients with ZX accompanied with obesity accepted EA treatment. Before and after 3-month treatment, observations were made on patients＆#39; fasting blood glucose （FBS）, fasting insulin （FINS）, in-sulin sensitivity index （ISI）, insulin resistance index （Homa-IR）, insulin secretion index （Homa-β）, degree of obesity （A）, body mass （Kg）, body mass index （BMI） and body fat percentage （F%） changes. The results showed that com-pared with pretreatment, the posttreatment FINS, Homa-IR, FBS had a significant decrease among 203 patients （P〈0.01）; the ISI and Homa-β had a significant increase （P 〈 0.01）. There was a significant statistical difference on islet β-cell function before and after treatment. The A, body mass, BMI, and F% were significantly decreased （P〈0.01）. It was concluded that EA can significantly correct ZX with obesity patients＆#39; glucose consumption, protect the islet β-cell function, and reduce the body mass of patients.