异丙嗪联合丹参川芎嗪治疗眩晕症的临床观察

Clinical observation of promethazine combined with salvia tetramethylpyrazine in treatment of patients with vertigo

目的：观察异丙嗪联合丹参川芎嗪治疗眩晕症的临床疗效。方法选择2011-02～2013-04该院收治的114例眩晕症患者随机分为治疗组和对照组各57例。治疗组给予盐酸异丙嗪，联合丹参川芎嗪治疗；对照组单用盐酸异丙嗪治疗。比较两组的临床疗效、症状消失时间、得分情况以及不良反应。结果治疗3d后，治疗组临床疗效高于对照组（P＜0.05）。治疗组的眩晕、植物神经症状、耳蜗综合征、前庭功能受损等症状消失时间均明显快于对照组（P＜0.01），症状得分明显低于对照组（P＜0.01）。两组不良反应均较轻微，采取相应措施后均消失。结论异丙嗪联合丹参川芎嗪治疗眩晕症的临床疗效显著，具有推广价值。

Objective To investigate the clinical effect of promethazine combined with salvia TMP in treat-ment of patients with vertigo .Methods The treatment group （ n=57 ） were treated with intramuscular injection of promethazine ,and intra venous injection of salvia tetramethylpy;The control group （ n=57 ） were treated with intra-muscular injection of promethazine only .Results After treatment for 3d,the total effective rate of the treatment group was significantly higher than that of the control group （ P〈0.05 ） .Symptoms disappearing time of vertigo , autonomic symptoms, cochlear syndrome , vestibular dysfunction and other symptoms of treatment group were significantly less than that of the control group ,symptoms scores of the treatment group was significantly lower than that of the control group（P〈0.01）.The adverse reactions of two groups were mild and disappeared after taking appropriate measures . Conclusion Clinical efficacy of promethazine combined with salvia TMP in treatment of patients with vertigo is sig -nificant .