妇科门诊1000例生殖道感染情况分析

Analysis of 1000 Cases of Reproductive Tract Infection in Gynecological Outpatient Service

目的:了解妇科门诊生殖道感染不同病原菌分布及耐药情况。方法:对笔者所在医院妇科门诊1000例生殖道感染患者的病原菌培养及药敏试验结果进行回顾性分析。结果:1000例标本检出菌株2039株,G+菌43.5%,G-菌22.4%,真菌16.4%,支原体13.2%,沙眼衣原体4.5%;前四位依次为大肠埃希菌13.9%(285/2039)、白色念珠菌13.8(281/2039)、支原体13.2%(270/2039)、表皮葡萄球菌13.0%(265/2039);大肠埃希菌对阿米卡星、亚胺培南、美洛培南均敏感,对复方磺胺、左氧氟沙星、环丙沙星、头孢吡肟、头孢呋辛、头孢他啶耐药性较高,白色念珠菌对5种抗真菌药物无耐药菌株,支原体对强力霉素、交沙霉素、克拉霉素耐药性较低。结论:研究女性生殖道感染病原体分布及耐药性对于临床合理使用抗菌药物,降低耐药率均具有积极意义。

Objective：To study the distribution and antibiotic resistance of reproductive tract infection pathogenic bacteria in gynecological outpatient.Method：The results of pathogenic bacteria cultivation and drug sensitive test of 1000 cases of reproductive tract infection patients from gynecological outpatient in our hospital were analysed.Result：2039 strains bacteria were detected from 1000 patients with reproductive tract infection,the Gram-positive bacteria accounted for 43.5%,and Gram-negative accounted for 22.4%,fungus accounted for 16.4%,mycoplasma accounted for 13.2%,Chlamydia trachomatis accounted for 4.5%.The top four bacteria were escherichia coli（13.9%）,candida albicans（13.8%）,mycoplasma（13.2%）,staphylococcus epidermidis（13.0%）.Escherichia coli was sensitive to Amikacin,Imipenem,Meropenem, and the resistance to Compound Sulfa-drugs and Levofloxacin,Ciprofloxacin,Cefepime,Cefuroxime,Cefotaxime were high.Candida albicans hadn＇t resistance to the 5 kinds of antifungal drugs.The resistance of Mycoplasma to Doxycycline,Josamycine,Clarithromycin were low.Conclusion：Studying of the female reproductive tract infection pathogens distribution and drug resistance has positive meaning to clinical rational use of antimicrobial and to reduce drug resistance.