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胱抑素C测定对高血压肾病早期诊断的临床价值 被引量:2

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摘要 目的分析胱抑素C测定对高血压肾病早期诊断的临床价值。方法选择2013年1-11月在该院住院和门诊确诊为高血压肾病的66例患者为观察组,并按照世界卫生组织/国际高血压联盟血压分级标准分为Ⅰ级25例(Ⅰ级组)、Ⅱ级22例(Ⅱ级组)、Ⅲ级19例(Ⅲ级组)。选择同期到该院进行健康体检的60例健康人员设为对照组。各组人员均进行胱抑素C水平测定,同时测定肾功能相关常规指标(尿素、肌酐),比较测定结果并进行分析。结果观察组患者的胱抑素C、尿素和肌酐水平较对照组均有明显升高,差异有统计学意义(P〈0.05),且随着病情的发展,其3项指标水平呈现逐步升高的趋势。观察组各组患者胱抑素C测定结果显示的阳性率均在80.0%以上,Ⅰ级组患者的胱抑素C阳性率均明显高于同组尿素和肌酐阳性率,差异有统计学意义(P〈0.05),但在Ⅱ级、Ⅲ级组中患者3项指标阳性率比较,差异均无统计学意义(P〉0.05)。结论胱抑素C是一种诊断高血压肾病较为敏感的有效血清指标,对于该疾病的诊断、病情监测和预后都有一定的临床价值。
出处 《现代医药卫生》 2014年第19期2981-2982,共2页 Journal of Modern Medicine & Health
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