摘要
目的:优选清半夏的炮制工艺。方法:以浸出物、总酸及白矾质量分数为指标,通过正交试验考察药材-白矾的质量比、浸泡时间、水煮时间对清半夏炮制工艺的影响。结果:优选的炮制工艺为浸泡2 h,水煮6 h,药材-白矾质量比10∶1;总酸、浸出物、白矾平均质量分数依次为0.83%,10.5%,6.4%。结论:总酸、浸出物及白矾含量均符合2010年版《中国药典》对清半夏的要求,清半夏粉末中草酸钙针晶明显减少,说明通过水煮炮制可降低半夏的毒性和刺激性,与传统工艺相比缩短了炮制时间。
Objective: To optimize processing technology of Pinelliae Rhizoma Praeparatum Cum Alumine. Method: Taking mass fractions of extract, total acids and Alumen as indexes, orthogonal test was adopted to optimize processing technology with mass ratio of herbs to Alumen, soaking time and decocting time as factors. Result: Optimum processing technology was that soaked 2 hours, boiled 6 hours, ratio of herbs to Alumen of 10: 1; mass fractions of extract, total acids and Alumen were 0. 83%, 10.5% and 6.4%, respectively. Conclusion: Contents of extract, total acids and Alumen are in line with requirements of Pinelliae Rhizoma Praeparatum Cum Alumine in the 2010 edition of ' Chinese Pharmacopoeia' , calcium oxalate crystals significantly reduce, this study show that water decoction process can reduce toxicity and irritation of Pinelliae Rhizoma with a relatively short time by comparing with conventional processing technology.
出处
《中国实验方剂学杂志》
CAS
北大核心
2014年第19期25-28,共4页
Chinese Journal of Experimental Traditional Medical Formulae
关键词
清半夏
总有机酸
浸出物
白矾
Pinelliae Rhizoma Praeparatum Cure Alumine
total acid
extract
Alumen