丁卡因胶浆对喉罩通气全麻苏醒期患者血流动力学的影响

Effect of tetracaine mucilage on hemodynamics of patients with laryngeal mask airway during recovery period of general anesthesia

目的：观察丁卡因胶浆涂抹喉罩对全麻患者血流动力学和咽部不适的影响。方法选择择期ASAⅠ～Ⅱ手术患者80例，随机分为观察组和对照组。观察组在一次性喉罩的前端和背面均匀涂抹盐酸丁卡因胶浆，对照组在相应位置涂抹石蜡油。观察并记录手术结束时（ T1）及拔出喉罩1 min（ T2）、3 min（ T3）和5 min（ T4）各时点的收缩压（ SBP）、舒张压（ DBP）、心率（ HR）的变化。并记录术后咽喉部不适、疼痛、声音嘶哑等并发症的发生率。结果两组在T1时刻HR、SBP和DBP水平比较差异无统计学意义（P﹥0.05）。与A组相比，B组在T2、T3、T4时刻SBP和DBP明显升高，HR增快（P﹤0.05）。A组术后咽喉部不适、疼痛、声音嘶哑的发生率明显低于B组（P﹤0.05）。结论应用丁卡因胶浆涂抹喉罩可以维持全麻苏醒期患者血流动力学的稳定，减轻咽喉部不适。

Objective To observe the effects of tetracaine mucilage coated laryngeal mask on hemodynamics and throat discomfort of patients with general anesthesia. Methods Eighty ASAⅠ-Ⅱ patients were randomly divided into observation group and control group. The patients in observation group were given tetracaine mucilage coated on the front and back of the laryngeal mask,and the patients in the control group were given sterile paraffin oil coated on the front and back of the laryngeal mask. The changes of SBP,DBP and HR were recorded at the end of the operation,1 minute,3 minutes and 5 minutes after the removal of the laryngeal mask. The incidences of complications such as post-operative throat discomfort,pain and hoarseness were recorded. Results There were no significant differences in levels of SBP,DBP and HR between the two groups at T1（P﹥0. 05）. The levels of SBP,DBP and HR were higher in group B than those in group A at T2,T3 and T4（P﹤0. 05）. The incidences of postoperative throat discomfort,pain and hoarseness in group A was lower than that in group B（P﹤0. 05）. Conclusions Application of tetracaine mucilage coated laryngeal mask can maintain the stable hemodynamics in patients during recovery period of general anesthesia,and relieve throat discomfort.