男性乳腺癌的病例对照研究

A Case-control Study on Male Breast Cancer

本文报告对40例男性乳腺癌病例的配对对照研究。资料经非条件Logistic回归模型分析显示膳食习惯是与该病发生有关的主要因素,肉类摄入过多者较易发生该病,水果、植物油摄入量多则有保护作用。结核病史与男性乳腺癌的联系也得到了证实。

Forty cases of male 5feast cancer were collected, which accounted for sixty-two per cent of all registered cases of 8 urban districts in Shanghai since 1960's. Each case was randomly matched with one or two nearest neighbour controls. The Cases and their fifty controls were inquired at their homes. and twenty-five cases were still alive then. Their birth date, education, marriage status, average income, occupation, living condition, hobby, dietary habits, exposure to x-ray and other chemical substances and their own and family medical history were reported. Mantel-Haenszle chi-square test, monovariable analysis were done by using unconditional Logistic regression. Then, fourteen variables were included in the multivariable Logistic regression model. The results showed that dietary habits was still the main risk factor of developing male breast cancer, especially the over intake of meat(OR=6.12, F=0.007). Fruits (OR=4.36, P=0.012) and vegetable oil(OR=5.86, P=0.005) intake had preventive effects from developing that cancer. The association between history of suffering from tuberculosis (OR=8.58, P=0.047) and this cancer was proved in this study.