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脑肾素(原)受体与神经源性高血压 被引量：2

The brain(pro)renin receptor in neurogenic hypertension
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摘要 脑肾素血管紧张素系统(RAS)在高血压的发展中起着重要的作用,主要是通过调节自主神经活性和血管加压素的释放来发挥作用。然而,脑是如何合成血管紧张素Ⅱ,长期以来存在争议,主要归究于中枢神经系统的低肾素活性。本文对新发现的RAS组分:脑肾素(原)受体,在调节血管紧张素Ⅱ形成和高血压的发展中的研究进展进行综述。 The brain renin-angiotensin system （RAS） plays an essential role in the development of hypertension, mainly through the modulation of autonomic activity and vasopressin release. However, how the brain synthesizes angiotensin II has long been a matter of debate, largely due to the low renin activity in the central nervous system. This review describes recent findings on the role of the brain （pro）renin receptor, a newly discovered component of the RAS-in mediating angiotensin II formation and hypertension development.
作者 Yumei Feng
机构地区 Department of Biomedical Sciences
出处 《中华高血压杂志》 CAS CSCD 北大核心 2014年第8期705-707,共3页 Chinese Journal of Hypertension
关键词 肾素原 肾素(原)受体 肾素血管紧张素系统 神经源性高血压 Prorenin （pro） Renin receptor Renin-angiotensin system Neurogenic hypertension
分类号 R544.1 [医药卫生—心血管疾病]
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参考文献43

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同被引文献32

  • 1林善锬.肾素-血管紧张素系统认识的演变及其临床意义[J].中华高血压杂志,2007,15(z1):3-5. 被引量：5
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中华高血压杂志
2014年 第8期

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