期刊文献+

危重病性肌病/危重病性多发性神经病的临床研究进展 被引量:9

下载PDF
导出
摘要 危重病性肌病(CIM)和危重病性多发性神经病(CIP)是ICU患者的严重并发症之一,临床表现为弛缓性肢体无力和呼吸机撤离困难。CIM和/或CIP使患者机械通气时间延长、死亡率升高,并可导致长期功能障碍。其危险因素包括严重的基础疾病、多脏器功能衰竭、高血糖等。近期临床研究结果认为CIM和CIM合并CIP较CIP更多见。神经电生理检查是诊断CIM和/或CIP重要依据,直接肌肉刺激(DMS)可鉴别CIP和CIM。CIM的预后好于CIP及CIM合并CIP。CIM和/或CIP的预防和治疗方法包括减少四肢肌肉和呼吸肌制动、早期积极治疗败血症、早期肠内营养、强化胰岛素治疗和肌肉电刺激治疗等。
出处 《国际神经病学神经外科学杂志》 2014年第4期356-359,共4页 Journal of International Neurology and Neurosurgery
基金 南方医科大学南方医院院长基金(2013Z003)
  • 相关文献

参考文献14

  • 1Lacomis D. Electmphysiology of neuromuscular disorders in critical illness. Muscle Nerve, 2013 , 47 ( 3 ) : 452-463.
  • 2Argov Z, Latronico N. Neuromuscular complications in inten-sive care patients. Handbook Clin Neurol, 2014, 121 (108) : 1673-1685.
  • 3Lacomis D. Neuromuscular disorders in critically ill patients: Review and update. J Clin Neuremusc Dis, 2011, 12 (4) : 197-218.
  • 4Ydemann M, Eddelien HS, Lauritsen AO. Treatment of criti- cal illness polyneurepathy and/or myopathy-a systematic re- view. Danish Med J, 2012, 59(10) : 1-7.
  • 5Khan J, Harrison TB, Rich MM. Mechanisms of neuromus- cular dysfunction in critical illness. Crit Care Clin, 2008, 24(1) : 165-177.
  • 6Koch S, Spuler S, Deja M, et al. Critical illness myopathy is frequent: Accompanying neuropathy protracts icu dis- charge. J Neurel Neurosurg Psychiatry, 2011 , 82 ( 3 ) : 287 -293.
  • 7Semmler A, Okulla T, Kaiser M, et al. Long-term neuro- muscular sequelae of critical illness. J Neurol, 2013 , 260 (2) : 151-157.
  • 8Weber-Carstens S, Deja M, Koch S, et al. Risk factors in critical illness myopathy during the early course of critical ill- ness : A prospective observational study. Crit Care, 2010,14(3): R119.
  • 9Latronico N, Bolton CF. Critical illness polyneuropathy and myopathy: A major cause of muscle weakness and paralysis. Lancet Neurol, 2011, 10(10): 931-941.
  • 10Eikermann M, Latronico N. What is new in prevention of muscle weakness in critically ill patients ? Intens Care Med, 2013, 39(12) : 2200-2203.

同被引文献46

引证文献9

二级引证文献43

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部