摘要
Stimuli-responsive polymers have the extraordinary ability to change their physical and/or chemical state after they‘‘detect’’a change in their environment;their response depends dramatically on their chemical composition.This property has been used for a plethora of applications;this review highlights their utility for human health.Specifically,this review will highlight efforts in the areas of sensing and biosensing,antimicrobial/antifouling coatings,tissue engineering and regenerative medicine,and drug delivery.Specific examples are given in each of these areas,with some focus on our work engineering poly(Nisopropylacrylamide)-based microgels and other responsive systems.
Stimuli-responsive polymers have the extraor- dinary ability to change their physical and/or chemical state after they ＂detect＂ a change in their environment; their response depends dramatically on their chemical compo- sition. This property has been used for a plethora of applications; this review highlights their utility for human health. Specifically, this review will highlight efforts in the areas of sensing and biosensing, antimicrobial/antifouling coatings, tissue engineering and regenerative medicine, and drug delivery. Specific examples are given in each of these areas, with some focus on our work engineering poly（N- isopropylacrylamide）-based microgels and other respon- sive systems.
基金
Michael J.Serpe acknowledges funding from the University of Alberta(the Department of Chemistry and the Faculty of Science)
the Natural Sciences and Engineering Research Council of Canada(NSERC)
the Canada Foundation for Innovation(CFI)
the Alberta Advanced Education&Technology Small Equipment Grants Program(AET/SEGP),IC-IMPACTS,and Grand Challenges Canada
关键词
聚合物材料
刺激响应性
人体健康
应用
N-异丙基丙烯酰胺
化学状态
生物传感
组织工程
Responsive polymers ； Poly（N-isopropylacrylamide） ； Sensing and biosensing - Drugdelivery - Antibacterial coatings - Tissue engineeringand regenerative medicine
