Smart Clip自锁托槽和传统托槽对正畸牙龈沟液中炎症因子水平的影响研究

Comparative study on inflammatory cytokine levels in gingival crevicular fluid during orthodontic tooth movement with Smart Clip self-ligating brackets and conventional brackets

目的探讨自锁矫治器和传统矫治器对牙齿加力后龈沟液中炎症因子水平变化从而比较两种类型托槽引起的牙周组织改建的情况。方法选择16例上颌前突需拔除上颌双侧第一前磨牙的患者,上牙列一侧使用自锁矫治器作为试验组,一侧使用传统直丝弓矫治器作为对照组,对两侧尖牙加力后取不同时间点的龈沟液,检测其中IL-1β和PGE2水平,分析其变化与牙周组织炎症反应的关系。结果在对尖牙加力后,龈沟液中IL-1β和PGE2水平均升高,均在加力后24 h达到最高值,各检测时间点试验组和对照组龈沟液中IL-1β和PGE2含量差异无统计学意义(P﹥0.05)。结论 2种矫治器在正畸牙移动的初期对牙周组织改建的影响无明显区别。

Objective To investigate changes of the cytokine levels in the gingival crevicular fluid after applying force on the self-ligating brackets and conventional brackets,and analyse the periodontal tissue remodeling. Methods Sixteen maxillary protruding patients who needed removing bilateral maxillary first premolars were selected,self-ligating appliance being used on one side of the upper dentition as the experimental group,and using traditional straight wire appliance on the other side as the control group. IL-1β and PGE2 levels of the gingival crevicular fluid taken at different time points in canine retraction were detected,and to analyze the relationship of their changes with periodontal tissue inflammatory response. Results After retruding the canines,levels of IL-1β and PGE2 of the gingival crevicular fluid all increased and reached their top at 24 h. There were no significant differencesin IL-1β and PGE2 levels of the gingival crevicular fluid between the experimental group and control group. Conclusions Self-ligating appliance did not differ significantly from traditional appliance in periodontal tissue remodeling in the early phase of the orthodontic tooth movement.