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手术治疗成人松果体区脊索样脑膜瘤1例

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摘要 患者女性,34岁,因头痛、头晕2个月余,加重伴行走不稳于2010年2月湖北医药学院附属太和医院收治入院。神经系统体检除闭目难立征闭眼阳性外,无其他阳性体征。颅脑MRI示:松果体区团块状异常信号,T1呈等或混杂信号(图1A),T2 FLAIR呈高信号(图1B),大小约2.0 cm×3.5 cm×2.1 cm,中脑导水管受压闭塞,双侧脑室及第三脑室扩大,周围脑组织受压。增强扫描见病变呈明显强化,边界清楚。诊断考虑为松果体肿瘤,生殖细胞瘤首先考虑并幕上梗阻性脑积水。2010年3月手术采用全麻下坐位通过幕下小脑上入路(Krause入路)行肿瘤切除术,术中见肿瘤质地较脆,灰白色,局部有钙化,两侧与丘脑粘连紧密,无明显边界及包膜,行次全切。病理示:松果体区脊索样脑膜瘤(WHOⅡ级)(图2)。免疫组织化学示:Vimentin(+),S-100(+),EMA(+), GFAP(-),CD34(-)。术后患者2周后治愈出院,未行放化疗,随访2年肿瘤无复发。
出处 《中国肿瘤临床》 CAS CSCD 北大核心 2014年第18期1202-1202,共1页 Chinese Journal of Clinical Oncology
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