金黄色葡萄球菌生物膜形成机制研究进展

Progress on Mechanism of Staphylococcus aureus Biofilm Formation

金黄色葡萄球菌是医院和社区获得性感染最常见的病原菌之一,而且可形成生物膜,从而导致生物膜相关疾病的产生。患者一旦发生金黄色葡萄球菌生物膜感染,难以彻底治愈。深入研究金黄色葡萄球菌生物膜形成的分子机制和调控网络,对寻找有效的防治、治疗药物和手段具有重要意义。我们就金黄色葡萄球菌生物膜形成过程和调控机制的研究近况做一综述。

Staphylococcus aureus is one of the most common pathogens in community acquired infection and nosocomial infection, and the biofilm formed by S.aureus can lead to biofilm associated diseases which are difficult to be completely cured. Well-understood molecular mechanisms and regulatory networks of S.aureus biofilm formation will greatly contribute to develop effective prevention and treatment medicines or approaches. In this article, we conducted a review of recent research on S.aureus biofilm formation and regulatory mechanisms.